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  1. pharmadog
  2. ›drugs
  3. ›patritumab deruxtecan
drug · antibody drug conjugate
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patritumab deruxtecan

Phase 3updated 3mo ago
by Daiichi Sankyo Co Ltd🔗 ChEMBL
Phase 3
community read0 votes

Antibody drug conjugate drug with a maximum clinical stage of Approval (across all indications), with an approval for neoplasm and 6 investigational indications.

indications

indications
NSCLC

targets

Receptor tyrosine-protein kinase erbB-3DNA topoisomerase 1

all catalysts(0)

nothing on the calendar yet

Trials studying patritumab deruxtecan

  • phase3A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)recruitingn=1,000
  • phase2A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)recruitingn=140
  • phase2Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)recruitingn=180
  • phase2Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)recruitingn=160
  • phase2A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)recruitingn=50
  • phase2HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Canceractive not recruitingn=277
  • phase2Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)recruitingn=372
  • phase2HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Diseaseactive not recruitingn=63
more trials →

News(2)

  • Daiichi’s pipeline falls behind rivals as cash flow nears peak: analysts
    With Enhertu and Datroway hitting their peak revenue and rivals flowing into the antibody-drug conjugate space, Jefferies cuts expectations for Daiichi Sankyo.
    biospace · 16d ago
  • Breast Cancer Experts Preview Abstracts to Watch at the 2026 ESMO Breast Cancer Congress
    Experts in a range of breast cancer subtypes highlight research data being presented at the 2026 ESMO Breast Cancer Congress.
    onclive · 3mo ago
generic
patritumab deruxtecan
MOA
Receptor tyrosine-protein kinase erbB-3 binding agent; DNA topoisomerase I inhibitor
indication
Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer)
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 2m ago
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