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  1. pharmadog
  2. ›drugs
  3. ›NINTEDANIB
drug · small molecule
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nintedanib

Phase 3updated 3mo ago
by Cloudbreak Therapeutics LLC🔗 ChEMBL
Phase 3
community read0 votes

🐶 often sniffed alongside

top 4
  • tagApproval10 co-mentions · 5 sources
  • tagSmall Molecule5 co-mentions · 5 sources
  • drugOfev5 co-mentions · 5 sources
  • drugNINTEDANIB ESYLATE5 co-mentions · 5 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 33 investigational indications.

indications

indications
Pulmonary Fibrosis

targets

Platelet-derived growth factor receptorVascular endothelial growth factor receptorFibroblast growth factor receptor

all catalysts(0)

nothing on the calendar yet

Trials studying nintedanib

  • phase2Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With Idiopathic Pulmonary Fibrosisrecruitingn=210
  • —Post-marketing Surveillance on Long Term Use of Ofev Capsules in Systemic Scleroderma Associated Interstitial Lung Disease (SSc-ILD) in Japancompletedn=586
  • phase1A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MNKD-201 in Patients With Idiopathic Pulmonary Fibrosiscompletedn=27
  • —Correlation Between Changes in Lung Function and Changes in Cough and Dyspnoea in Nintedanib-treated Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) Patientsterminatedn=88
  • phase1A Study to Evaluate Pharmacokinetics and Drug-drug Interactions of ENV-101 (Taladegib) in Healthy Participantsrecruitingn=57
  • phase1Study on the Drug Interactions of HRS-9813, Pirfenidone and Nintedanib in Healthy Subjectsrecruitingn=20
  • —Real-life-persistence to Antifibrotic Treatmentscompletedn=10,646
  • phase2Phase II Study of Docetaxel +/- Nintedanib in Breast Cancercompletedn=51
more trials →

News(2)

  • A PureTech startup banks $180M for a new IPF drug
    Celea, backed by investors such as RA Capital and Leaps by Bayer, is making what it says is an improved version of Roche's Esbriet.
    biopharma_dive · 1mo ago
  • Avalyn, in pursuit of better lung drugs, banks $300M in an IPO
    The biotech will use the proceeds to develop inhalable versions of therapies already on the market for the “idiopathic” and “progressive” forms of pulmonary fibrosis.
    biopharma_dive · 3mo ago
brand
NINTEDANIB
trade names
Nintedanib component of ofev, Ofev, Vargatef
generic
nintedanib
MOA
Platelet-derived growth factor receptor inhibitor; Vascular endothelial growth factor receptor inhibitor; Fibroblast growth factor receptor inhibitor
indication
Pterygium
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 41m ago
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