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  1. pharmadog
  2. ›drugs
  3. ›Lunsumio Velo
drug · antibody
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mosunetuzumab

Marketedupdated 5mo ago
by Genentech Inc🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • drugLUNSUMIO12 co-mentions · 3 sources
  • tagApproval12 co-mentions · 3 sources
  • companyGenentech Inc6 co-mentions · 3 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for neoplasm and follicular lymphoma and 4 investigational indications.

indications

investigational
DLBCL

targets

B-lymphocyte antigen CD20T cell surface glycoprotein CD3

all catalysts(3)

approval · 3
Dec 22, 2022
approval
4y ago
LUNSUMIO (MOSUNETUZUMAB-AXGB) — FDA approval
mosunetuzumab
→
Nov 22, 2024
approval
2y ago
LUNSUMIO (MOSUNETUZUMAB-AXGB) — FDA approval
mosunetuzumab
→
Dec 19, 2025
approval
10mo ago
LUNSUMIO (MOSUNETUZUMAB-AXGB) — FDA approval
mosunetuzumab
→

Trials studying mosunetuzumab

  • phase2A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritisrecruitingn=30
  • phase2Phase 2 Study Of Mosunetuzumab In Patients With Chronic Lymphocytic Leukemia With Positive MRDrecruitingn=30
  • phase1A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphomaactive not recruitingn=121
  • phase3A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphomaactive not recruitingn=208
  • phase1A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemiarecruitingn=332
  • phase2Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL Trialrecruitingn=22
  • phase2A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignanciesrecruitingn=80
  • phase2Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphomarecruitingn=30

News(6)

  • Genentech makes $1.5B+ deal with AI heavyweight Earendil for cancer bispecifics
    Genentech's agreement with Earendil Labs came the same day its parent company, Roche, inked a cardiometabolic and renal deal with Atavistik Bio for up to $2 billion.
    biospace · 5d ago
  • Ultragenyx prices Sanfilippo gene therapy at $4M; Bristol Myers shelves Orum drug
    Ultragenyx’s second gene therapy approval since August gives it another sellable voucher. Elsewhere, Roche declared success in a blood cancer trial and a cell therapy maker is cutting costs.
    biopharma_dive · 12d ago
  • Roche eyes label expansion for Lunsumio after confirmatory lymphoma trial win
    Roche’s T cell engager Lunsumio has passed a Phase 3 trial in a slow-growing type of blood cancer, clearing the path for full approval and a broader label. Lunsumio is a bispecific antibody that ta…
    endpoints · 13d ago
  • Roche bets up to $1B to advance next-gen bispecifics with Dualitas
    The partners will focus R&D efforts on immunological and inflammatory conditions using Dualitas’ DualScreen Bispecific Discovery Engine platform.
    biospace · 13d ago
  • Roche, Dualitas team up to find bispecific drugs for immune diseases
    Through a research deal worth up to $1 billion, Dualitas will sift through more than 300,000 possible bispecific combinations in the hopes of unearthing new and differentiating treatments.
    biopharma_dive · 13d ago
  • Roche signs $1B deal with Dualitas to pair up on big bispecific screening drive
    Roche is paying Dualitas Therapeutics $36.5 million upfront to screen over 300,000 novel bispecific combinations in search of new treatments for immunology and inflammation diseases.
    fiercebiotech · 13d ago
brand
Lunsumio Velo
trade names
Lunsumio
generic
mosunetuzumab-axgb
MOA
B-lymphocyte antigen CD20 binding agent; T cell surface glycoprotein CD3 binding agent
indication
Diffuse Large B-Cell Lymphoma
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 3h ago
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