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  1. pharmadog
  2. ›drugs
  3. ›Midostaurin
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midostaurin

Marketedupdated 3mo ago
by Lupin Ltd
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Trials studying midostaurin

  • phase2A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AMLactive not recruitingn=22
  • phase3Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AMLcompletedn=214
  • phase1Revumenib in Combination With 7+3 + Midostaurin in AMLrecruitingn=22
  • phase2Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC)recruitingn=214
  • phase2Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemiaactive not recruitingn=181
  • phase2A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AMLcompletedn=67
  • phase3A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapyactive not recruitingn=777
  • phase2Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemiawithdrawn
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Oct 9, 2028
~2.1 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Dec 2, 2030method-of-use (U-2008)US 85751464.3y
  • Oct 9, 2028method-of-use (U-2007)US 79730312.1y

News(0)

no news has mentioned this drug yet

brand
Midostaurin
generic
midostaurin
indication
Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia)
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 36m ago
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