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  1. pharmadog
  2. ›drugs
  3. ›Zokinvy
drug
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lonafarnib

Marketedupdated 3mo ago
by Sentynl Therapeutics Inc
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Trials studying lonafarnib

  • phase3Once Daily Dosing of Lonafarnib Co-administered With Ritonavir for Treatment of Chronic Hepatitis D Virus Infectioncompletedn=10
  • phase2Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)active not recruitingn=10
  • phase2Titrating-Dose of Lonafarnib in Combination With Ritonavircompletedn=15

Patent cliff

source: FDA Orange Book
first barrier falls
Nov 20, 2027
~1.3 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Jul 26, 2029method-of-use (U-3070)US 78385312.9y
  • Jul 26, 2029method-of-use (U-3070)US 78385312.9y

FDA exclusivities (2)

  • Nov 20, 2027ODE-324Orphan Drug (7y)1.3y
  • Nov 20, 2027ODE-324Orphan Drug (7y)1.3y

News(1)

  • Zydus’ Sentynl pens $475M deal for Mereo’s phase 3-ready rare genetic lung disease drug
    Sentynl Therapeutics has penned a deal potentially worth $475 million for the option to market Mereo BioPharma's phase 3-ready rare genetic respiratory disease drug in the U.S.
    fiercebiotech · 7d ago
brand
Zokinvy
generic
lonafarnib
indication
Hutchinson-Gilford Progeria
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 28m ago
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