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  1. pharmadog
  2. ›drugs
  3. ›LIDOCAINE
drug · small molecule
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LIDOCAINE

Marketedupdated 3mo ago
by MEDRx Co Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval330 co-mentions · 137 sources
  • druglidocaine SR278 co-mentions · 174 sources
  • drugLIDOCAINE HYDROCHLORIDE AND EPINEPHRINE238 co-mentions · 81 sources
  • drugLIDOCAINE HYDROCHLORIDE236 co-mentions · 140 sources
  • drugAKTEN228 co-mentions · 139 sources
  • drugLinisol223 co-mentions · 139 sources
  • drugLaryng-O-Jet223 co-mentions · 139 sources
  • drugLIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5%223 co-mentions · 139 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 21 approved and 110 investigational indications.

targets

Sodium channel alpha subunit

all catalysts(5)

approval · 1
Feb 9, 2026
approval
6mo ago
LIDOCAINE — FDA approval
LIDOCAINE
→
phase 2 completion · 3
Apr 27, 2026
phase 2 completion
4mo ago
Sustained Therapeutics Inc — lidocaine SR (Phase II Trial Completion)
LIDOCAINE
→
Apr 30, 2026
phase 2 completion
3mo ago
Huadong Hospital Affiliated to Fudan University — lidocaine (Phase II Trial Completion)
LIDOCAINE
→
Apr 30, 2026
phase 2 completion
3mo ago
Cairo University — lidocaine (Phase II Trial Completion)
LIDOCAINE
→
phase 3 completion · 1
Apr 25, 2026
phase 3 completion
4mo ago
Ain Shams University — lidocaine (Phase III Trial Completion)
LIDOCAINE
→

Trials studying LIDOCAINE

  • N/AEfficacy and Safety of Rejuviel V in the Correction of Midface Volume Deficitcompletedn=89
  • phase1Bioequivalence Study of Lidocaine and Prilocaine Cream in Healthy Chinese Subjectscompletedn=40
  • phase4Workflow Optimization During Pulse Field Ablation for Atrial Fibrillationnot yet recruitingn=60
  • phase3Saypha® VOLUME Lidocaine for Midface Augmentationcompletedn=562
  • phase4Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injectionsenrolling by invitationn=236
  • phase3Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Morphine-rachi Analgesianot yet recruitingn=76
  • phase2A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Paincompletedn=63
  • —Prospective, Non-interventional Study Assessing Periorbital Rejuvenation Procedurecompletedn=29
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Sep 24, 2028
~2.1 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (8)

  • May 10, 2031formulationUS 107656404.7y
  • May 10, 2031formulationUS 107657494.7y
  • May 10, 2031formulationUS 112786234.7y
  • May 10, 2031formulationUS 117864554.7y
  • May 10, 2031method-of-use (U-2267)US 117937664.7y
  • May 10, 2031formulationUS 92831744.7y
  • May 10, 2031formulationUS 99252644.7y
  • May 10, 2031formulationUS 99314034.7y

FDA exclusivities (1)

  • Sep 24, 2028NPNP2.1y

News(3)

  • Convenience Kit Correction: Medline Issues Correction for Kits Containing Huons Lidocaine Hydrochloride and Bupivacaine Hydrochloride in Dextrose Injection
    Medline is correcting affected convenience kits by removing recalled Lidocaine Hydrochloride and Bupivacaine Hydrochloride in Dextrose Injection components from affected convenience kits.
    fda_medwatch · 8d ago
  • Convenience Kit Correction: Argon Medical Issues Correction for Convenience Kits Containing Spectra Medical Device Lidocaine Ampules
    Argon Medical is correcting affected convenience kits by removing included Spectra Medical Devices Lidocaine Ampules.
    fda_medwatch · 12d ago
  • Convenience Kit Correction: Arrow International Issues Correction for Convenience Kits Containing Recalled Huons Lidocaine and Bupivacaine and Saline
    Saline, Lidocaine and Bupivacaine from affected convenience kits should not be used.
    fda_medwatch · 26d ago
brand
LIDOCAINE
trade names
Alphacaine, Dentipatch, Lidocaine, Lidocaine component of emla, Lidocaine component of fortacin, Lidocaine component of lanabiotic
generic
LIDOCAINE
MOA
Sodium channel alpha subunit blocker
indication
Postherpetic Neuralgia
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 17m ago
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