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  2. ›drugs
  3. ›LEUCOVORIN CALCIUM
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LEUCOVORIN CALCIUM

Marketedupdated 3mo ago
by Avyxa Pharma LLC
Approved
community read0 votes

🐶 often sniffed alongside

top 5
  • tagApproval12 co-mentions · 6 sources
  • drugWELLCOVORIN10 co-mentions · 6 sources
  • drugVYKOURA7 co-mentions · 6 sources
  • drugLeucovorin Calcium Teva6 co-mentions · 6 sources
  • tagSmall Molecule4 co-mentions · 4 sources

all catalysts(6)

approval · 6
Jul 8, 1983
approval
43y ago
WELLCOVORIN (LEUCOVORIN CALCIUM) — FDA approval
LEUCOVORIN CALCIUM
→
Apr 14, 1993
approval
33y ago
WELLCOVORIN (LEUCOVORIN CALCIUM) — FDA approval
LEUCOVORIN CALCIUM
→
Jun 6, 1996
approval
30y ago
WELLCOVORIN (LEUCOVORIN CALCIUM) — FDA approval
LEUCOVORIN CALCIUM
→
Nov 12, 2025
approval
9mo ago
LEUCOVORIN CALCIUM — FDA approval
LEUCOVORIN CALCIUM
→
Feb 3, 2026
approval
7mo ago
VYKOURA (LEUCOVORIN CALCIUM) — FDA approval
LEUCOVORIN CALCIUM
→
Mar 9, 2026
approval
5mo ago
WELLCOVORIN (LEUCOVORIN CALCIUM) — FDA approval
LEUCOVORIN CALCIUM
→

Trials studying LEUCOVORIN CALCIUM

  • phase2A Study of MRG007 Combination Therapy for Advanced Colorectal Cancernot yet recruitingn=316
  • phase1A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapyrecruitingn=36
  • phase3A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancerrecruitingn=1,000
  • phase3A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapyrecruitingn=700
  • phase2A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemiacompletedn=171
  • phase3Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescentsactive not recruitingn=560
  • phase2Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinomarecruitingn=56
  • phase2A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancerterminatedn=247
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Dec 23, 2044
~18.4 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (3)

  • Dec 23, 2044formulationUS 12564592
  • Dec 23, 2044formulationUS 12564592
  • Dec 23, 2044formulationUS 12564592

News(0)

no news has mentioned this drug yet

brand
LEUCOVORIN CALCIUM
generic
LEUCOVORIN CALCIUM
indication
Metastatic Colorectal Cancer
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 17m ago
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