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  1. pharmadog
  2. ›drugs
  3. ›leronlimab
drug · antibody
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leronlimab

Phase 2updated 5mo ago
by $CYDY CytoDyn Inc.🔗 ChEMBL
Phase 2
community read0 votes

Antibody drug with a maximum clinical stage of Phase 3 (across all indications), with 7 investigational indications.

indications

indications
NSCLCMelanoma

targets

C-C chemokine receptor type 5

all catalysts(0)

nothing on the calendar yet

Trials studying leronlimab

  • phase2CLOVER - CCR5-targeting Leronlimab With Oral Chemotherapy and VEGF-inhibitor Enriched Regimenactive not recruitingn=66
  • —An Open-Label, Multicenter, Non-Randomized Expanded Access Protocol (EAP) Designed to Provide Leronlimab to Patients With Locally Advanced or Metastatic Triple-Negative Breast Cancer (mTNBC)available
  • phase2Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumorscompletedn=16
  • phase2Evaluate the Efficacy & Safety of Leronlimab in Patients With Severe or Critical COVID-19completedn=484
  • phase2Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBCterminatedn=10
  • —A Compassionate Use Study of Leronlimab in Breast Cancerno longer available
  • phase2Double Blind, Placebo Controlled Study of Safety and Efficacy of Leronlimab in Patients With "Long" COVID-19completedn=56

News(1)

  • CytoDyn’s leronlimab reaffirms HIV potential after combo treatment eradicates virus in infant macaques
    CytoDyn's leronlimab may have struggled to secure approval as an HIV treatment, but research in infant primates has offered fresh hope for the CCR5-targeting antibody's ability to treat the virus.
    fiercebiotech · 1mo ago
generic
leronlimab
MOA
C-C chemokine receptor type 5 antagonist
indication
Metabolic Dysfunction-Associated Steatohepatitis (MASH or NASH)
phase
phase_2
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 1h ago
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