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  1. pharmadog
  2. ›drugs
  3. ›Lenvima
drug · small molecule
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lenvatinib mesylate

Marketedupdated 3mo ago
by Eisai Co Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 7
  • tagOncology18 co-mentions · 2 sources
  • companyEisai Co Ltd2 co-mentions · 2 sources
  • tagInfectious Disease2 co-mentions · 2 sources
  • tagBreast Cancer2 co-mentions · 2 sources
  • tagColorectal Cancer2 co-mentions · 2 sources
  • tagMelanoma2 co-mentions · 2 sources
  • druglenvatinib2 co-mentions · 2 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 4 approved and 2 investigational indications.

indications

investigational
Colorectal CancerMelanoma

targets

Vascular endothelial growth factor receptor

all catalysts(2)

drug expiry · 1
Apr 24, 2026
drug expiry
4mo ago
Eisai Co Ltd — lenvatinib mesylate (Drug Expiry (US))
lenvatinib mesylate
→
patent expiry · 1
Apr 24, 2026
patent expiry
4mo ago
Eisai Co Ltd — lenvatinib mesylate (Constraining Patent Expiry (US))
lenvatinib mesylate
→

Trials studying lenvatinib mesylate

  • phase2Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinomaactive not recruitingn=18

Patent cliff

source: FDA Orange Book
first barrier falls
Sep 19, 2026
30 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (40)

  • Nov 15, 2038patentUS 12226409*PED
  • Nov 15, 2038patentUS 12226409*PED
  • May 15, 2038method-of-use (U-4146)US 12226409
  • May 15, 2038method-of-use (U-4146)US 12226409
  • Sep 3, 2036patentUS 12083112*PED
  • Sep 3, 2036patentUS 12083112*PED
  • Aug 23, 2036patentUS 11090386*PED
  • Aug 23, 2036patentUS 11090386*PED
  • Mar 3, 2036method-of-use (U-3997)US 12083112
  • Mar 3, 2036method-of-use (U-3997)US 12083112
  • Feb 26, 2036patentUS 10259791*PED
  • Feb 26, 2036patentUS 10259791*PED
  • Feb 26, 2036patentUS 10407393*PED
  • Feb 26, 2036patentUS 10407393*PED
  • Feb 26, 2036patentUS 11186547*PED
  • Feb 26, 2036patentUS 11186547*PED
  • Feb 23, 2036method-of-use (U-3519)US 11090386
  • Feb 23, 2036method-of-use (U-3519)US 11090386
  • Aug 26, 2035compositionUS 10259791
  • Aug 26, 2035compositionUS 10259791
  • Aug 26, 2035compositionUS 10407393
  • Aug 26, 2035compositionUS 10407393
  • Aug 26, 2035compositionUS 11186547
  • Aug 26, 2035compositionUS 11186547
  • Apr 4, 2031patentUS 12508313*PED4.6y
  • Apr 4, 2031patentUS 12508313*PED4.6y
  • Oct 4, 2030formulationUS 125083134.1y
  • Oct 4, 2030formulationUS 125083134.1y
  • Jan 27, 2028patentUS 9006256*PED1.4y
  • Jan 27, 2028patentUS 9006256*PED1.4y
  • Jul 27, 2027method-of-use (U-1695)US 9006256341d
  • Jul 27, 2027method-of-use (U-1695)US 9006256341d
  • Mar 19, 2027patentUS 7612208*PED211d
  • Mar 19, 2027patentUS 7612208*PED211d
  • Sep 19, 2026compositionUS 761220830d
  • Sep 19, 2026compositionUS 761220830d
  • Apr 24, 2026patentUS 7253286*PED
  • Apr 24, 2026patentUS 7253286*PED
  • Oct 24, 2025compositionUS 7253286
  • Oct 24, 2025compositionUS 7253286

FDA exclusivities (8)

  • Oct 3, 2027PEDPediatric (6mo bonus)1.1y
  • Oct 3, 2027PEDPediatric (6mo bonus)1.1y
  • Apr 3, 2027M-14Method (3y)226d
  • Apr 3, 2027M-14Method (3y)226d
  • Feb 15, 2026PEDPediatric (6mo bonus)
  • Feb 15, 2026PEDPediatric (6mo bonus)
  • Aug 15, 2025ODE-196Orphan Drug (7y)
  • Aug 15, 2025ODE-196Orphan Drug (7y)

News(0)

no news has mentioned this drug yet

brand
Lenvima
trade names
Kisplyx, Lenvima
generic
lenvatinib mesylate
MOA
Vascular endothelial growth factor receptor inhibitor
indication
Renal Cell Carcinoma
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 2m ago
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