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  1. pharmadog
  2. ›drugs
  3. ›KESIMPTA
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KESIMPTA

Marketedupdated 3mo ago
by $NVS NOVARTIS AG🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval52 co-mentions · 13 sources
  • drugofatumumab27 co-mentions · 14 sources
  • companyHenan Provincial People's Hospital1 co-mentions · 1 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 17 investigational indications.

targets

B-lymphocyte antigen CD20

all catalysts(13)

approval · 13
Oct 26, 2009
approval
$NVS150.88-0.55%
17y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Sep 23, 2010
approval
$NVS150.88-0.55%
16y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Sep 20, 2011
approval
$NVS150.88-0.55%
15y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Sep 24, 2013
approval
$NVS150.88-0.55%
13y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Apr 17, 2014
approval
$NVS150.88-0.55%
12y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Jan 19, 2016
approval
$NVS150.88-0.55%
11y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Aug 30, 2016
approval
$NVS150.88-0.55%
10y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Aug 20, 2020
approval
$NVS150.88-0.55%
6y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Sep 2, 2022
approval
$NVS150.88-0.55%
4y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Jan 19, 2024
approval
$NVS150.88-0.55%
3y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Apr 12, 2024
approval
$NVS150.88-0.55%
2y ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Aug 18, 2025
approval
$NVS150.88-0.55%
12mo ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
Apr 1, 2026
approval
$NVS150.88-0.55%
5mo ago
KESIMPTA (OFATUMUMAB) — FDA approval
KESIMPTA
→
view all 13 catalysts →

Trials studying KESIMPTA

  • —A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosisrecruitingn=800
  • —Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumabenrolling by invitationn=75
  • —A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babiesactive not recruitingn=1,178
  • —Assessment of the Quality of Life of Multiple Sclerosis Patients Treated With Ofatumumab in Real-life in Franceactive not recruitingn=302
  • phase3Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumabactive not recruitingn=196
  • —Kesimpta® (Ofatumumab) in Swiss Multiple Sclerosis Patients - an Observational Studycompletedn=107
  • —ITAKOS - Italian Observation, Multicenter, Prospective Study of Ofatumumab in RRMS Patientsactive not recruitingn=379
  • phase3An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumabcompletedn=562
more trials →

News(2)

  • Novartis climbs on upbeat drug sales as key readouts loom
    A return to quarterly sales growth boosted shares higher on Tuesday, though a handful of coming study results will have a bigger impact on the company’s long-term outlook.
    biopharma_dive · 24d ago
  • Novartis stays 'geography-agnostic' in dealmaking amid flurry of China deals
    Novartis will continue to be on the lookout for bolt-on deals below $2 billion, CEO Vas Narasimhan said Tuesday on the pharma's second quarter earnings call—though major pickups aren’t completely o…
    biospace · 24d ago
brand
KESIMPTA
trade names
Arzerra, Kesimpta
generic
OFATUMUMAB
MOA
12.1 Mechanism of Action The precise mechanism by which ofatumumab exerts its therapeutic effects in multiple sclerosis is unknown, but is presumed to involve binding to CD20, a cell surface antigen present on pre-B and mature B lymphocytes. Following cell surface binding to B lymphocytes, ofatumumab results in antibody-dependent cellular cytolysis and complement-mediated lysis.
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 20m ago
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