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  1. pharmadog
  2. ›drugs
  3. ›Tremfya
drug · antibody
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guselkumab

Marketedupdated 3mo ago
by $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • drugTREMFYA56 co-mentions · 14 sources
  • tagApproval56 co-mentions · 14 sources
  • companyJanssen Biotech Inc28 co-mentions · 14 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 6 approved and 15 investigational indications.

indications

investigational
IBD (Crohn's + UC)

targets

Interleukin-23

all catalysts(14)

approval · 14
Jul 13, 2017
approval
9y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Jan 29, 2019
approval
8y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Apr 4, 2019
approval
7y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Nov 22, 2019
approval
7y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Jun 1, 2020
approval
6y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Jul 13, 2020
approval
6y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Jun 29, 2023
approval
3y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Sep 11, 2024
approval
2y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Mar 20, 2025
approval
1y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Mar 25, 2025
approval
1y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Jun 17, 2025
approval
1y ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Sep 19, 2025
approval
11mo ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Sep 26, 2025
approval
11mo ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Sep 26, 2025
approval
11mo ago
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
view all 14 catalysts →

Trials studying guselkumab

  • phase3A Study of Guselkumab in Participants With Active Psoriatic Arthritisactive not recruitingn=1,054
  • —Efficacy and Safety of Guselkumab in Patients With Moderate-to-Severe Ulcerative Colitisrecruitingn=97
  • phase3A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitisrecruitingn=644
  • phase3A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Diseaserecruitingn=460
  • phase4A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Diseaseactive not recruitingn=411
  • phase4A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)recruitingn=100
  • phase3A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Diseaseactive not recruitingn=350
  • phase3A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Diseaserecruitingn=120
more trials →

News(9)

  • MoonLake’s nanobody boosts all clinical endpoints in phase 3 psoriatic arthritis trial
    MoonLake Immunotherapeutics announced positive phase 3 data for patients with psoriatic arthritis treated with its lead nanobody candidate, sonelokimab.
    fiercebiotech · 10d ago
  • J&J dips despite upbeat outlook; AstraZeneca, Spero cut China deals
    J&J’s shares ticked down as oncology sales missed expectations. Elsewhere, AstraZeneca bet $600 million on a lung cancer drug and a pair of biotechs snagged two of the year’s top venture rounds.
    biopharma_dive · 1mo ago
  • Fresh off buyout, Akero execs reunite to advance long-acting psoriasis pill
    Set to go public via a reverse merger, Avere has licensed from a prolific Chinese drugmaker rights to a potential threat to medicines like Skyrizi and Icotyde.
    biopharma_dive · 1mo ago
  • Takeda’s $4B TYK2 drug tops Bristol Myers’ Sotyktu in head-to-head test
    The results support Takeda’s long-held belief in zasocitinib’s superiority and could help it gain a commercial advantage over Bristol’s therapy.
    biopharma_dive · 2mo ago
  • AstraZeneca seeks path for failed antibody; Imfinzi, Tremfya get label expansions
    🔎 AstraZeneca narrows path for failed antibody: The company announced last summer that its monoclonal antibody anselamimab missed the primary endpoint in a pair of Phase 3 trials for patients with…
    endpoints · 2mo ago
  • Avalo shares spike on skin drug data; BioNTech to cut staff
    Avalo reported study success in what’s proven to be a tough-to-treat skin disease. Elsewhere, BioNTech announced plans to close multiple plants and Madrigal picked up an RNA-based drug for MASH.
    biopharma_dive · 3mo ago
  • J&J's IBD combo fails Phase 2 studies, but will move into pivotal testing
    Johnson & Johnson will move a treatment for inflammatory bowel disease into Phase 3 studies despite the therapy's failure in two mid-stage trials. The company said that JNJ-4804, a combination of t…
    endpoints · 3mo ago
  • STAT+: Pharmalittle: We’re reading about RFK Jr. targeting antidepressants, J&J pushing an IBD drug, and more
    HHS Secretary Robert F. Kennedy Jr. announced initiatives to rein in prescribing of SSRIs, the most widely used antidepressants
    stat · 3mo ago
  • STAT+: Johnson & Johnson advances IBD therapy, despite trial miss
    A closely watched therapy developed by Johnson & Johnson failed to show a statistically meaningful improvement for IBD patients.
    stat · 3mo ago
brand
Tremfya
trade names
Tremfya
generic
guselkumab
MOA
Interleukin-23 inhibitor
indication
Psoriatic Arthritis
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 38m ago
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