drug · antibody
guselkumab
Marketedupdated 3mo agoby $JNJ JOHNSON & JOHNSON🔗 ChEMBL
Approvedcommunity read0 votes
🐶 often sniffed alongside
top 3Antibody drug with a maximum clinical stage of Approval (across all indications), with 6 approved and 15 investigational indications.
indications
investigational
IBD (Crohn's + UC)
targets
Interleukin-23
all catalysts(14)
approval · 14
Jul 13, 2017
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Jan 29, 2019
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Apr 4, 2019
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Nov 22, 2019
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Jun 1, 2020
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Jul 13, 2020
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Jun 29, 2023
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Sep 11, 2024
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Mar 20, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Mar 25, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Jun 17, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Sep 19, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
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Sep 26, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Sep 26, 2025
approval
TREMFYA (GUSELKUMAB) — FDA approval
guselkumab
→
Trials studying guselkumab
- phase3A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
- phase3A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
- phase4A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease
- phase4A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)
- phase3A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease
- phase3A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
- phase3A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
- phase3A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
News(9)
- MoonLake’s nanobody boosts all clinical endpoints in phase 3 psoriatic arthritis trialMoonLake Immunotherapeutics announced positive phase 3 data for patients with psoriatic arthritis treated with its lead nanobody candidate, sonelokimab.fiercebiotech · 4d ago
- J&J dips despite upbeat outlook; AstraZeneca, Spero cut China dealsJ&J’s shares ticked down as oncology sales missed expectations. Elsewhere, AstraZeneca bet $600 million on a lung cancer drug and a pair of biotechs snagged two of the year’s top venture rounds.biopharma_dive · 1mo ago
- Fresh off buyout, Akero execs reunite to advance long-acting psoriasis pillSet to go public via a reverse merger, Avere has licensed from a prolific Chinese drugmaker rights to a potential threat to medicines like Skyrizi and Icotyde.biopharma_dive · 1mo ago
- Takeda’s $4B TYK2 drug tops Bristol Myers’ Sotyktu in head-to-head testThe results support Takeda’s long-held belief in zasocitinib’s superiority and could help it gain a commercial advantage over Bristol’s therapy.biopharma_dive · 2mo ago
- AstraZeneca seeks path for failed antibody; Imfinzi, Tremfya get label expansions🔎 AstraZeneca narrows path for failed antibody: The company announced last summer that its monoclonal antibody anselamimab missed the primary endpoint in a pair of Phase 3 trials for patients with…endpoints · 2mo ago
- Avalo shares spike on skin drug data; BioNTech to cut staffAvalo reported study success in what’s proven to be a tough-to-treat skin disease. Elsewhere, BioNTech announced plans to close multiple plants and Madrigal picked up an RNA-based drug for MASH.biopharma_dive · 3mo ago
- J&J's IBD combo fails Phase 2 studies, but will move into pivotal testingJohnson & Johnson will move a treatment for inflammatory bowel disease into Phase 3 studies despite the therapy's failure in two mid-stage trials. The company said that JNJ-4804, a combination of t…endpoints · 3mo ago
- STAT+: Pharmalittle: We’re reading about RFK Jr. targeting antidepressants, J&J pushing an IBD drug, and moreHHS Secretary Robert F. Kennedy Jr. announced initiatives to rein in prescribing of SSRIs, the most widely used antidepressantsstat · 3mo ago
- STAT+: Johnson & Johnson advances IBD therapy, despite trial missA closely watched therapy developed by Johnson & Johnson failed to show a statistically meaningful improvement for IBD patients.stat · 3mo ago
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