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  1. pharmadog
  2. ›drugs
  3. ›Columvi
drug · antibody
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glofitamab

Marketedupdated 3mo ago
by F. Hoffmann-La Roche Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • drugCOLUMVI12 co-mentions · 3 sources
  • tagApproval12 co-mentions · 3 sources
  • companyGenentech Inc6 co-mentions · 3 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for neoplasm and diffuse large b-cell lymphoma and 6 investigational indications.

indications

investigational
DLBCL

targets

B-lymphocyte antigen CD20T cell surface glycoprotein CD3

all catalysts(3)

approval · 3
Jun 15, 2023
approval
3y ago
COLUMVI (GLOFITAMAB-GXBM) — FDA approval
glofitamab
→
Jun 9, 2025
approval
1y ago
COLUMVI (GLOFITAMAB-GXBM) — FDA approval
glofitamab
→
Oct 27, 2025
approval
10mo ago
COLUMVI (GLOFITAMAB-GXBM) — FDA approval
glofitamab
→

Trials studying glofitamab

  • phase1A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphomaactive not recruitingn=121
  • phase2A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphomaactive not recruitingn=940
  • phase2A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphomarecruitingn=100
  • phase2An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphomaactive not recruitingn=211
  • phase2Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse Large B Cell Lymphomanot yet recruitingn=40
  • phase3A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphomarecruitingn=182
  • —An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphomarecruitingn=300
  • phase2A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphomarecruitingn=65
more trials →

News(0)

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brand
Columvi
trade names
Columvi
generic
glofitamab-gxbm
MOA
B-lymphocyte antigen CD20 binding agent; T cell surface glycoprotein CD3 binding agent
indication
Mantle Cell Lymphoma
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 7m ago
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