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  1. pharmadog
  2. ›drugs
  3. ›Vabysmo
drug · antibody
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faricimab

Marketedupdated 5mo ago
by F. Hoffmann-La Roche Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval20 co-mentions · 5 sources
  • drugVABYSMO20 co-mentions · 5 sources
  • companyGenentech Inc10 co-mentions · 5 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 5 investigational indications.

indications

investigational
Diabetic Macular Edema

targets

Angiopoietin-2Vascular endothelial growth factor A, long form

all catalysts(5)

approval · 5
Jan 28, 2022
approval
5y ago
VABYSMO (FARICIMAB-SVOA) — FDA approval
faricimab
→
Jan 27, 2023
approval
4y ago
VABYSMO (FARICIMAB-SVOA) — FDA approval
faricimab
→
Oct 26, 2023
approval
3y ago
VABYSMO (FARICIMAB-SVOA) — FDA approval
faricimab
→
Jul 3, 2024
approval
2y ago
VABYSMO (FARICIMAB-SVOA) — FDA approval
faricimab
→
Apr 9, 2026
approval
6mo ago
VABYSMO (FARICIMAB-SVOA) — FDA approval
faricimab
→

Trials studying faricimab

  • phase3Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDRrecruitingn=426
  • —A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Productsactive not recruitingn=6,000
  • phase4A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edemaactive not recruitingn=218
  • phase4A Prospective Longitudinal Analysis of Faricimab (Vabysmo 6mg) For Choroidal Neovascularization in Presumed Ocular Histoplasmosis Syndromerecruitingn=25
  • phase3Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathyrecruitingn=600
  • phase3A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopiacompletedn=280
  • —A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)recruitingn=850
  • phase4A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degenerationactive not recruitingn=274

News(10)

  • Kodiak skyrockets on positive study data for 2 eye drugs
    The Phase 3 findings suggested Kodiak might have multiple threats to Regeneron’s Eylea and added more than $3 billion to the company’s market value.
    biopharma_dive · 4h ago
  • Genentech makes $1.5B+ deal with AI heavyweight Earendil for cancer bispecifics
    Genentech's agreement with Earendil Labs came the same day its parent company, Roche, inked a cardiometabolic and renal deal with Atavistik Bio for up to $2 billion.
    biospace · 3d ago
  • Merck sees pivotal victory for $3B eye disease prospect
    Merck & Co.’s Brunello trial has hit its primary endpoint, shedding light on the effects of a trispecific diabetic macular edema (DME) drug candidate that the Big Pharma bought in a $3 billion take…
    fiercebiotech · 4d ago
  • Roche bets up to $1B to advance next-gen bispecifics with Dualitas
    The partners will focus R&D efforts on immunological and inflammatory conditions using Dualitas’ DualScreen Bispecific Discovery Engine platform.
    biospace · 11d ago
  • Roche, Dualitas team up to find bispecific drugs for immune diseases
    Through a research deal worth up to $1 billion, Dualitas will sift through more than 300,000 possible bispecific combinations in the hopes of unearthing new and differentiating treatments.
    biopharma_dive · 11d ago
  • Roche signs $1B deal with Dualitas to pair up on big bispecific screening drive
    Roche is paying Dualitas Therapeutics $36.5 million upfront to screen over 300,000 novel bispecific combinations in search of new treatments for immunology and inflammation diseases.
    fiercebiotech · 11d ago
  • EyePoint plummets on pivotal data for main drug
    Though its drug missed the key goal of a wet AMD study, EyePoint — as well as analysts — see a path toward approval. Investors may be harder to win over, however.
    biopharma_dive · 1mo ago
  • FDA scientists question Capricor data; Legend CEO steps down
    Capricor shares lost much of their value ahead of a high-stakes advisory committee meeting. Elsewhere, Ying Huang’s resignation extended a stock slide for Legend and AstraZeneca disclosed more pipe…
    biopharma_dive · 2mo ago
  • Roche's late stage pipeline 'so full,' CEO Schinecker not feeling pressure to add on
    Roche has 19 investigational medicines that could launch by 2030—and even if not all of them make it to market, the company is “well set-up for growth into the next decade,” CEO Thomas Schinecker s…
    biospace · 2mo ago
  • Roche drops TCE for lupus, but hasn’t given up on autoimmune cell therapies
    Roche may have scrapped work on a T-cell engager being evaluated for lupus, but the company’s head of pharma told Fierce that still has a strategy for developing cell therapies for autoimmune disea…
    fiercebiotech · 2mo ago
view all news mentions →
brand
Vabysmo
trade names
Vabysmo
generic
faricimab-svoa
MOA
Angiopoietin-2 inhibitor; Vascular endothelial growth factor A inhibitor
indication
Choroidal Neovascularization
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 1h ago
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