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  1. pharmadog
  2. ›drugs
  3. ›etavopivat
drug · small molecule
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etavopivat

Phase 3updated 3mo ago
by Novo Nordisk AS🔗 ChEMBL
Phase 3
community read0 votes

Small molecule drug with a maximum clinical stage of Phase 3 (across all indications), with 4 investigational indications.

indications

indications
Sickle Cell Disease

targets

Pyruvate kinase PKLR

all catalysts(0)

nothing on the calendar yet

Trials studying etavopivat

  • phase2A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Diseaserecruitingn=95
  • phase3A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Diseaserecruitingn=408
  • phase2Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Diseasecompletedn=12
  • phase3A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)active not recruitingn=450
  • phase3A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemiarecruitingn=480
  • phase1A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participantscompletedn=33
  • phase1A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participantscompletedn=24
  • phase2A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Diseasecompletedn=53
more trials →

News(3)

  • Biotechs bring big launches and pharma rivalries into Q2 earnings period
    With the second quarter earnings period underway, BioSpace examines five biotechs with meaningful catalysts that analysts and investors are watching.
    biospace · 22d ago
  • Agios axes next-gen sickle cell candidate after it fails to best Novo’s asset
    Agios Pharmaceuticals’ sickle cell disease candidate didn’t prove any better than Novo Nordisk’s investigational PK activator or the biopharma’s own asset that is currently under FDA review for the…
    biospace · 1mo ago
  • Agios says adios to sickle cell program over lackluster phase 2 data
    A phase 2 study of Agios Pharmaceuticals’ next-generation pyruvate kinase activator has failed to support continued development in sickle cell disease, leading the company to ax an indication for t…
    fiercebiotech · 1mo ago
generic
etavopivat
MOA
Pyruvate kinase isozymes R/L activator
indication
Sickle Cell Disease
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 42m ago
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