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  1. pharmadog
  2. ›drugs
  3. ›Bkemv
drug
save

eculizumab biosimilar

Marketedupdated 3mo ago
by $AMGN AMGEN INC
Approved
community read0 votes

🐶 often sniffed alongside

top 4
  • drugBKEMV14 co-mentions · 7 sources
  • tagApproval14 co-mentions · 7 sources
  • company$AMGNAMGEN INC7 co-mentions · 7 sources
  • drugeculizumab7 co-mentions · 7 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 5 approved and 20 investigational indications.

all catalysts(7)

approval · 7
May 28, 2024
approval
$AMGN415.21-0.63%
2y ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Oct 23, 2024
approval
$AMGN415.21-0.63%
2y ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Jan 30, 2025
approval
$AMGN415.21-0.63%
2y ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Apr 18, 2025
approval
$AMGN415.21-0.63%
1y ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Sep 17, 2025
approval
$AMGN415.21-0.63%
11mo ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Nov 24, 2025
approval
$AMGN415.21-0.63%
9mo ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→
Mar 26, 2026
approval
$AMGN415.21-0.63%
5mo ago
BKEMV (ECULIZUMAB-AEEB) — FDA approval
eculizumab biosimilar
→

Trials studying eculizumab biosimilar

  • phase3A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuriacompletedn=50

News(0)

no news has mentioned this drug yet

brand
Bkemv
generic
ECULIZUMAB-AEEB
MOA
12.1 Mechanism of Action Eculizumab-aeeb, the active ingredient in BKEMV, is a monoclonal antibody that specifically binds to the complement protein C5 with high affinity, thereby inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9. Eculizumab products inhibit terminal complement-mediated intravascular hemolysis in PNH patients and complement-mediated thrombotic microangiopathy (TMA) in patients with aHUS. The precise mechanism by which eculizumab exerts its therapeutic effect in gMG patients is unknown, but is presumed to involve reduction of terminal complement complex C5b-9 deposition at the neuromuscular junction.
indication
Paroxysmal Nocturnal Hemoglobinuria
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 17m ago
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