drug · antibody
dupilumab
Marketedupdated 5mo agoby $REGN REGENERON PHARMACEUTICALS, INC.🔗 ChEMBL
Approvedannual revenue · 2024–2024peak $14.1B
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🐶 often sniffed alongside
top 7Antibody drug with a maximum clinical stage of Approval (across all indications), with 8 approved and 30 investigational indications.
indications
investigational
Asthma
targets
Interleukin-4 receptor subunit alpha
all catalysts(33)
approval · 31
Mar 28, 2017
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 10, 2018
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 10, 2018
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 19, 2018
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Mar 11, 2019
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 26, 2019
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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May 26, 2020
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2020
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2020
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 14, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 1, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 20, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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May 20, 2022
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 7, 2022
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 28, 2022
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 17, 2022
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jul 14, 2023
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 29, 2023
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 12, 2024
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 25, 2024
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 12, 2024
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 12, 2024
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 27, 2024
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 16, 2025
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 17, 2025
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2025
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Feb 23, 2026
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 16, 2026
approval
$REGN790.74-0.70%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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pdufa · 1
Trials studying dupilumab
- phase3Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
- phase1An Active Comparator Safety Study Evaluating the Combination of APG777 + APG990 in Moderate-to-Severe Atopic Dermatitis
- phase3A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in Asthma
- —Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study
- phase3A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
- phase4A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
- phase2Study to Assess Efficacy and Safety of Dupilumab in the Treatment of Keloids
- —A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in Germany
News(10)
- Pharma’s $500B patent problem will come in waves — not as a cliffMerck is the most vulnerable to generic competition in the short term, but AbbVie, Johnson & Johnson, Sanofi and others will also grapple with patent losses in the years to come.biopharma_dive · 6d ago
- Bausch + Lomb swaps CEOs; Merck reveals anticipated eye drug dataBausch and Brent Saunders “mutually agreed” on his exit from the company, according to a statement. Elsewhere, Tezspire could have a new edge on Dupixent and a recent buyout deal paid dividends.biopharma_dive · 6d ago
- Genmab and AbbVie’s Epkinly win, a rush of deals, Sarepta’s turnaround hopes, moreNew data for Genmab and AbbVie’s bispecific antibody Epkinly wowed analysts and could set the partners up for an expanded approval in diffuse large B cell lymphoma; deals have flowed steadily this…biospace · 11d ago
- The top biopharma conferences in 2027Medical meetings often feature important clinical trial results, making them barometers of biotech and pharma companies’ research progress. Here’s a list of conferences to watch for in 2027.biopharma_dive · 12d ago
- Lilly, Foghorn part ways; Wave’s FDA-approved plansThe pharma giant cut its partnership after a cancer drug disappointed in testing. Elsewhere, Teva and Samsung Bioepis expanded a partnership and space biotech Varda brought in $251 million.biopharma_dive · 17d ago
- Sanofi, Regeneron broaden alliance to find their next DupixentThe deal carries a $1 billion upfront payment and tasks the two companies to develop long-acting antibody drugs that go after the same targets as their blockbuster anti-inflammation agent.biopharma_dive · 17d ago
- Pfizer’s eczema drug clears skin in mid-stage trialDetailed results are competitive with Dupixent and Ebglyss, but the drug lacks differentiation amid an increasingly competitive landscape, one analyst argued.biopharma_dive · 17d ago
- Sanofi pays Regeneron $1B upfront to continue search for Dupixent successorSanofi and Regeneron have had a long and “sometimes contentious” partnership, BMO Capital Markets noted, as the companies contend with the looming loss of exclusivity of their blockbuster drug Dupi…biospace · 17d ago
- Sanofi builds on immunology alliance with Regeneron for $1B upfrontAs the patent cliff for Dupixent draws closer, Sanofi is turning back to the partnership that built the megablockbuster. The French pharma will pay $1 billion upfront to expand its antibody collabo…endpoints · 17d ago
- STAT+: Sanofi, Regeneron expand partnership after Dupixent successSanofi and Regeneron have re-upped their collaboration pact, aiming to build on the blockbuster success of the drug Dupixent.stat · 17d ago
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