drug · antibody
dupilumab
Marketedupdated 4mo agoby $REGN REGENERON PHARMACEUTICALS, INC.🔗 ChEMBL
Approvedannual revenue · 2024–2024peak $14.1B
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🐶 often sniffed alongside
top 7Antibody drug with a maximum clinical stage of Approval (across all indications), with 8 approved and 30 investigational indications.
indications
investigational
Asthma
targets
Interleukin-4 receptor subunit alpha
all catalysts(33)
approval · 31
Mar 28, 2017
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 10, 2018
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 10, 2018
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 19, 2018
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Mar 11, 2019
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 26, 2019
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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May 26, 2020
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2020
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2020
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 14, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 1, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 20, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Dec 22, 2021
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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May 20, 2022
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 7, 2022
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 28, 2022
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Oct 17, 2022
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jul 14, 2023
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 29, 2023
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 12, 2024
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jan 25, 2024
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 12, 2024
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 12, 2024
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Sep 27, 2024
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 16, 2025
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 17, 2025
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Jun 18, 2025
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Feb 23, 2026
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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Apr 16, 2026
approval
$REGN843.47-1.00%
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
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pdufa · 1
Trials studying dupilumab
- phase3Dupilumab in Allergic Fungal Rhinosinusitis (AFRS)
- —A Study to Observe How Pediatric Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions Respond to Dupilumab Treatment
- phase3Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)
- phase2A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)
- —The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis
- phase4The Effects of Dupilumab on Allergic Contact Dermatitis
- phase3A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)
- phase3A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid
News(10)
- AstraZeneca, Amgen poised to challenge Dupixent’s reign with esophagitis winEven without specific Phase 3 data yet revealed, analysts see AstraZeneca and Amgen’s Tezspire as a potential threat for Dupixent in eosinophilic esophagitis.biospace · 7d ago
- New data could widen use of AstraZeneca, Amgen immune disease drugTezspire succeeded in a study in eosinophilic esophagitis, which could become the drug’s third approved indication and unlock what’s viewed as a blockbuster opportunity.biopharma_dive · 7d ago
- Founded by Metsera backers, Sentivera emerges with $1.5B inflammatory disease dealHaving set Metsera on its journey to a $10 billion takeover, Arch Venture Partners and Population Health Partners have powered their new startup—Sentivera—to a licensing deal worth up to $1.5 billion.fiercebiotech · 10d ago
- Regeneron ends eye disease study due to antibody's safety profileThe discontinuation of the uveitis study adds to Regeneron’s series of clinical setbacks, including the Phase 3 failures of the Dupixent follow-up itepekimab and an investigational combo regimen fo…biospace · 17d ago
- Regeneron ends eye disease study due to antibody's safety profileThe discontinuation of the uveitis study adds to Regeneron’s series of clinical setbacks, including the Phase 3 failures of the Dupixent follow-up itepekimab and an investigational combo regimen fo…biospace · 17d ago
- Chasing Dupixent, a biotech aims to make better antibody drugs for eczemaInfinimmune, a California startup, is developing treatments it claims might last longer and be more effective than existing atopic dermatitis medications.biopharma_dive · 24d ago
- Regeneron backs $75M series A for antibody upstart InfinimmuneInfinimmune has amassed further fuel to power its antibody discovery engine, netting a $75 million series A headlined by Regeneron’s venture arm.fiercebiotech · 24d ago
- Braveheart pumps more life into biotech IPO market with $382M expected debutBraveheart Bio has emerged on the Nasdaq with an upsized expected initial public offering—marking the public entrance of the twenty-second biotech this year.biospace · 29d ago
- Sanofi pauses mid-stage lung study amid new CEO’s ‘rigorous portfolio prioritization’Since stepping in as Sanofi’s CEO in April, Belén Garijo has launched a deep look at the pharma’s pipeline, reassessing assets based on “scientific merit” and potential for long-term value in the q…biospace · 29d ago
- A COPD drug from China draws $115M in venture fundingExpedition Therapeutics, which has raised nearly $300 million to date, is studying a drug it believes to have notable advantages over other COPD treatments either in development or on the market.biopharma_dive · 1mo ago
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