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  1. pharmadog
  2. ›drugs
  3. ›Dupixent
drug · antibody
save

dupilumab

Marketedupdated 4mo ago
by $REGN REGENERON PHARMACEUTICALS, INC.🔗 ChEMBL
Approved
annual revenue · 2024–2024peak $14.1B
2024: $14.1B2024$14.1B
community read0 votes

🐶 often sniffed alongside

top 7
  • drugDUPIXENT126 co-mentions · 33 sources
  • tagApproval124 co-mentions · 31 sources
  • companyBrigham and Women's Hospital1 co-mentions · 1 sources
  • tagPulmonology1 co-mentions · 1 sources
  • tagDermatology1 co-mentions · 1 sources
  • tagAsthma1 co-mentions · 1 sources
  • tagPDUFA1 co-mentions · 1 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with 8 approved and 30 investigational indications.

indications

investigational
Asthma

targets

Interleukin-4 receptor subunit alpha

all catalysts(33)

approval · 31
Mar 28, 2017
approval
$REGN843.47-1.00%
9y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jan 10, 2018
approval
$REGN843.47-1.00%
9y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 10, 2018
approval
$REGN843.47-1.00%
8y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Oct 19, 2018
approval
$REGN843.47-1.00%
8y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Mar 11, 2019
approval
$REGN843.47-1.00%
7y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 26, 2019
approval
$REGN843.47-1.00%
7y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
May 26, 2020
approval
$REGN843.47-1.00%
6y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 18, 2020
approval
$REGN843.47-1.00%
6y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 18, 2020
approval
$REGN843.47-1.00%
6y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 14, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Oct 1, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Oct 20, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Dec 22, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Dec 22, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Dec 22, 2021
approval
$REGN843.47-1.00%
5y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
May 20, 2022
approval
$REGN843.47-1.00%
4y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 7, 2022
approval
$REGN843.47-1.00%
4y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Sep 28, 2022
approval
$REGN843.47-1.00%
4y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Oct 17, 2022
approval
$REGN843.47-1.00%
4y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jul 14, 2023
approval
$REGN843.47-1.00%
3y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Sep 29, 2023
approval
$REGN843.47-1.00%
3y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jan 12, 2024
approval
$REGN843.47-1.00%
3y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jan 25, 2024
approval
$REGN843.47-1.00%
3y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 12, 2024
approval
$REGN843.47-1.00%
2y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Sep 12, 2024
approval
$REGN843.47-1.00%
2y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Sep 27, 2024
approval
$REGN843.47-1.00%
2y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 16, 2025
approval
$REGN843.47-1.00%
1y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 17, 2025
approval
$REGN843.47-1.00%
1y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Jun 18, 2025
approval
$REGN843.47-1.00%
1y ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Feb 23, 2026
approval
$REGN843.47-1.00%
6mo ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
Apr 16, 2026
approval
$REGN843.47-1.00%
5mo ago
DUPIXENT (DUPILUMAB) — FDA approval
dupilumab
→
pdufa · 1
Apr 27, 2026
pdufa
$REGN843.47-1.00%
4mo ago
Regeneron Pharmaceuticals Inc — dupilumab (PDUFA)
dupilumab
→
phase 2 completion · 1
Apr 30, 2026
phase 2 completion
4mo ago
Brigham and Women's Hospital — dupilumab (Phase II Trial Completion)
dupilumab
→
view all 33 catalysts →

Trials studying dupilumab

  • phase3Dupilumab in Allergic Fungal Rhinosinusitis (AFRS)completedn=62
  • —A Study to Observe How Pediatric Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions Respond to Dupilumab Treatmentrecruitingn=230
  • phase3Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)enrolling by invitationn=90
  • phase2A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)terminatedn=256
  • —The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitisrecruitingn=184
  • phase4The Effects of Dupilumab on Allergic Contact Dermatitisactive not recruitingn=17
  • phase3A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)active not recruitingn=138
  • phase3A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoidcompletedn=106
more trials →

News(10)

  • AstraZeneca, Amgen poised to challenge Dupixent’s reign with esophagitis win
    Even without specific Phase 3 data yet revealed, analysts see AstraZeneca and Amgen’s Tezspire as a potential threat for Dupixent in eosinophilic esophagitis.
    biospace · 7d ago
  • New data could widen use of AstraZeneca, Amgen immune disease drug
    Tezspire succeeded in a study in eosinophilic esophagitis, which could become the drug’s third approved indication and unlock what’s viewed as a blockbuster opportunity.
    biopharma_dive · 7d ago
  • Founded by Metsera backers, Sentivera emerges with $1.5B inflammatory disease deal
    Having set Metsera on its journey to a $10 billion takeover, Arch Venture Partners and Population Health Partners have powered their new startup—Sentivera—to a licensing deal worth up to $1.5 billion.
    fiercebiotech · 10d ago
  • Regeneron ends eye disease study due to antibody's safety profile
    The discontinuation of the uveitis study adds to Regeneron’s series of clinical setbacks, including the Phase 3 failures of the Dupixent follow-up itepekimab and an investigational combo regimen fo…
    biospace · 17d ago
  • Regeneron ends eye disease study due to antibody's safety profile
    The discontinuation of the uveitis study adds to Regeneron’s series of clinical setbacks, including the Phase 3 failures of the Dupixent follow-up itepekimab and an investigational combo regimen fo…
    biospace · 17d ago
  • Chasing Dupixent, a biotech aims to make better antibody drugs for eczema
    Infinimmune, a California startup, is developing treatments it claims might last longer and be more effective than existing atopic dermatitis medications.
    biopharma_dive · 24d ago
  • Regeneron backs $75M series A for antibody upstart Infinimmune
    Infinimmune has amassed further fuel to power its antibody discovery engine, netting a $75 million series A headlined by Regeneron’s venture arm.
    fiercebiotech · 24d ago
  • Braveheart pumps more life into biotech IPO market with $382M expected debut
    Braveheart Bio has emerged on the Nasdaq with an upsized expected initial public offering—marking the public entrance of the twenty-second biotech this year.
    biospace · 29d ago
  • Sanofi pauses mid-stage lung study amid new CEO’s ‘rigorous portfolio prioritization’
    Since stepping in as Sanofi’s CEO in April, Belén Garijo has launched a deep look at the pharma’s pipeline, reassessing assets based on “scientific merit” and potential for long-term value in the q…
    biospace · 29d ago
  • A COPD drug from China draws $115M in venture funding
    Expedition Therapeutics, which has raised nearly $300 million to date, is studying a drug it believes to have notable advantages over other COPD treatments either in development or on the market.
    biopharma_dive · 1mo ago
view all news mentions →
brand
Dupixent
trade names
Dupixent, Regn668, sar231893
generic
dupilumab
MOA
Interleukin-4 receptor subunit alpha antagonist
indication
Chronic Urticaria
phase
marketed
approved
2017-03-28
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 3h ago
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