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  1. pharmadog
  2. ›drugs
  3. ›Darzalex
drug · antibody
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daratumumab

pre_registrationupdated 3mo ago
by $JNJ JOHNSON & JOHNSON🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 8
  • drugdaratumumab + Gene Therapy63 co-mentions · 18 sources
  • drugDARZALEX FASPRO60 co-mentions · 15 sources
  • tagApproval60 co-mentions · 15 sources
  • drug(daratumumab + hyaluronidase (human recombinant))31 co-mentions · 16 sources
  • companyJanssen Biotech Inc30 co-mentions · 15 sources
  • tagOncology3 co-mentions · 2 sources
  • tagImmunology2 co-mentions · 1 sources
  • tagHematology2 co-mentions · 1 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for multiple myeloma and neoplasm and 37 investigational indications.

targets

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

all catalysts(0)

nothing on the calendar yet

Trials studying daratumumab

  • phase3Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patientsrecruitingn=824
  • phase3A Study of the Efficacy and Safety of BCD-248 in Combination With Daratumumab in Patients With Relapsed or Refractory Multiple Myeloma (AMMADINA)recruitingn=390
  • phase1A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide or in Combination With Pomalidomide for Multiple Myelomarecruitingn=240
  • phase3A Study of Daratumumabactive not recruitingn=213
  • phase3A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myelomaactive not recruitingn=452
  • phase2Pan Tumor Rollover Studyrecruitingn=1,500
  • phase3A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myelomanot yet recruitingn=520
  • phase2A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myelomarecruitingn=246
more trials →

News(7)

  • Legend Biotech CEO abruptly steps down without permanent replacement
    In a sudden leadership shift, Legend Biotech announced that its CEO, Ying Huang, Ph.D., resigned on Friday, with no permanent replacement yet named.
    fiercebiotech · 15d ago
  • J&J dips despite upbeat outlook; AstraZeneca, Spero cut China deals
    J&J’s shares ticked down as oncology sales missed expectations. Elsewhere, AstraZeneca bet $600 million on a lung cancer drug and a pair of biotechs snagged two of the year’s top venture rounds.
    biopharma_dive · 27d ago
  • Medicare drug price rule may target under-the-skin Keytruda and Opdivo
    For 2029, a federal rule proposes closing a "loophole" that protects medicines transitioning from intravenous administration from price protection.
    biopharma_dive · 1mo ago
  • J&J multiple myeloma drug gains edge in earlier stage disease
    The latest results studying Talvey in combination with Darzalex Faspro support J&J’s efforts to expand the immunotherapy's use.
    biopharma_dive · 1mo ago
  • J&J to acquire Firefly, maker of ‘degrader’ antibody drugs, for $1B
    The buyout hands J&J a technology that merges elements of two popular drugmaking methods: protein degraders and antibody-drug conjugates.
    biopharma_dive · 2mo ago
  • 2026 Orphan Drugs Report: A safe(r) passage amid stormy waters?
    Orphan drugs remain commercially durable, strategically relevant and supported by a strong pipeline
    biopharma_dive · 2mo ago
  • FDA tests out ‘real-time’ clinical trials; AbbVie closes in on a KRAS biotech
    Through two pioneering studies, Amgen and AstraZeneca will share study data with FDA scientists as it’s accrued. Elsewhere, Lilly inked a gene editing deal and Pfizer reported success for a multipl…
    biopharma_dive · 3mo ago
brand
Darzalex
trade names
Daratumumab component of darzalex faspro, Darzalex
generic
daratumumab
MOA
Lymphocyte differentiation antigen CD38 inhibitor
indication
Multiple Myeloma (Kahler Disease)
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 18m ago
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