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  1. pharmadog
  2. ›drugs
  3. ›Vyxeos
drug
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(cytarabine hydrochloride + daunorubicin hydrochloride)

Marketedupdated 3mo ago
by $JAZZ Jazz Pharmaceuticals plc
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval10 co-mentions · 5 sources
  • drugcytarabine5 co-mentions · 5 sources
  • drugCytarabine Pfizer5 co-mentions · 5 sources

all catalysts(0)

nothing on the calendar yet

Trials studying (cytarabine hydrochloride + daunorubicin hydrochloride)

  • phase1CPX-351 in Combination With Gemtuzumab Ozogamicin in Newly Diagnosed AMLrecruitingn=18
  • phase1Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AMLrecruitingn=22
  • —VYxeoS Liposomal Italian Observational Study iN the Real Practicecompletedn=113
  • phase1Vyxeos® With Clofarabine for Pediatric AMLrecruitingn=25
  • N/AA Bioequivalence Study of (Cytarabine: Daunorubicin) Liposome for Injectionunknownn=36

Patent cliff

source: FDA Orange Book
first barrier falls
Jan 23, 2027
165 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (15)

  • Apr 15, 2033patentUS 10028912*PED
  • Apr 15, 2033patentUS 10166184*PED
  • Apr 15, 2033patentUS 10835492*PED
  • Oct 15, 2032formulationUS 10028912
  • Oct 15, 2032formulationUS 10166184
  • Oct 15, 2032method-of-use (U-3150)US 10835492
  • Oct 1, 2029patentUS 8092828*PED3.1y
  • Apr 1, 2029method-of-use (U-3147)US 80928282.6y
  • Mar 14, 2028patentUS 8022279*PED1.6y
  • Sep 14, 2027formulationUS 80222791.1y
  • Jul 23, 2027patentUS 7850990*PED346d
  • Jul 23, 2027patentUS 9271931*PED346d
  • Jan 23, 2027formulationUS 7850990165d
  • Jan 23, 2027formulationUS 9271931165d
  • Jun 7, 2026formulationUS 8518437

FDA exclusivities (2)

  • Sep 30, 2028PEDPediatric (6mo bonus)2.1y
  • Mar 30, 2028ODE-350Orphan Drug (7y)1.6y

News(0)

no news has mentioned this drug yet

brand
Vyxeos
generic
(cytarabine hydrochloride + daunorubicin hydrochloride)
indication
Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia)
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 1h ago
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