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  2. ›drugs
  3. ›Cyclophosphamide
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cyclophosphamide

Marketedupdated 3mo ago
by Long Grove Pharmaceuticals LLC
Approved
community read0 votes

🐶 often sniffed alongside

top 8
  • tagDLBCL6 co-mentions · 3 sources
  • tagOncology5 co-mentions · 4 sources
  • tagCLL4 co-mentions · 1 sources
  • companySandoz Inc2 co-mentions · 1 sources
  • tagHematology2 co-mentions · 1 sources
  • companyCity of Hope1 co-mentions · 1 sources
  • companyNational Cancer Institute US1 co-mentions · 1 sources
  • companyGeneral Hospital of the People's Liberation Army1 co-mentions · 1 sources

indications

investigational
Breast CancerDLBCL

all catalysts(3)

phase 1 2 completion · 2
Apr 25, 2026
phase 1 2 completion
4mo ago
General Hospital of the People's Liberation Army — cyclophosphamide (Phase I/II Trial Completion)
cyclophosphamide
→
Apr 30, 2026
phase 1 2 completion
3mo ago
Institute of Hematology & Blood Diseases Hospital — cyclophosphamide (Phase I/II Trial Completion)
cyclophosphamide
→
phase 2 initiation · 1
Apr 27, 2026
phase 2 initiation
4mo ago
National Cancer Institute US — cyclophosphamide (Phase II Trial Initiation)
cyclophosphamide
→

Trials studying cyclophosphamide

  • phase2Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphomaactive not recruitingn=129
  • phase1A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosisactive not recruitingn=10
  • phase3A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphomarecruitingn=822
  • phase3A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)recruitingn=960
  • phase2CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumorcompletedn=30
  • phase2A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphomarecruitingn=60
  • phase2A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)recruitingn=240
  • phase2A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)recruitingn=594
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Jun 26, 2035
~8.9 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (15)

  • Feb 15, 2036formulationUS 10993952
  • Feb 15, 2036formulationUS 10993952
  • Feb 15, 2036formulationUS 10993952
  • Feb 15, 2036formulationUS 12329767
  • Feb 15, 2036formulationUS 12329767
  • Feb 15, 2036formulationUS 12329767
  • Dec 1, 2035formulationUS 11382923
  • Dec 1, 2035formulationUS 11382923
  • Dec 1, 2035formulationUS 11382923
  • Jul 13, 2035formulationUS 10849916
  • Jul 13, 2035formulationUS 10849916
  • Jul 13, 2035formulationUS 10849916
  • Jun 26, 2035formulationUS 9662342
  • Jun 26, 2035formulationUS 9662342
  • Jun 26, 2035formulationUS 9662342

News(4)

  • Sunny Pharmtech, Inc. Issues Voluntary Nationwide Recall of Cyclophosphamide for Injection, USP to the User Level Due to the Presence of Particulate Matter
    July 24, 2026 - Taoyuan City, Taiwan - Sunny Pharmtech, Inc is voluntarily recalling three lots of Cyclophosphamide for Injection, USP, 1g/vial and 2g/vial, to the User Level due to the presence of…
    fda_medwatch · 19d ago
  • Neoadjuvant T-DXd Followed by THP Improves RCB in HER2+ Breast Cancer
    Treatment with neoadjuvant T-DXd followed by THP resulted in lower RCB vs ddAC-THP in patients with high-risk, HER2-positive early-stage breast cancer.
    onclive · 3mo ago
  • ASCO 2026 HR+ and HER2+ Breast Cancer Preview: Read up on the Insights to Know Before You Go
    Breast cancer experts spotlight the abstracts they’re most excited to see at the 2026 ASCO Annual Meeting.
    onclive · 3mo ago
  • Breast Cancer Experts Preview Abstracts to Watch at the 2026 ESMO Breast Cancer Congress
    Experts in a range of breast cancer subtypes highlight research data being presented at the 2026 ESMO Breast Cancer Congress.
    onclive · 3mo ago
brand
Cyclophosphamide
generic
cyclophosphamide [INN]
indication
Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia)
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 33m ago
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