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  1. pharmadog
  2. ›drugs
  3. ›Piasky
drug · antibody
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crovalimab

Phase 3updated 3mo ago
by F. Hoffmann-La Roche Ltd🔗 ChEMBL
Phase 3
community read0 votes

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for paroxysmal nocturnal hemoglobinuria and 4 investigational indications.

targets

Complement C5

all catalysts(0)

nothing on the calendar yet

Trials studying crovalimab

  • phase3A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)active not recruitingn=83
  • phase2A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)completedn=95
  • phase3A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)active not recruitingn=41
  • phase2A Study to Evaluate Crovalimab in People With Antiphospholipid Syndrome (APS)withdrawn
  • phase3A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitorsactive not recruitingn=210
  • phase2Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuriaactive not recruitingn=59
  • phase3A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitionactive not recruitingn=51
  • phase3A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitorsactive not recruitingn=190
more trials →

News(0)

no news has mentioned this drug yet

brand
Piasky
trade names
Piasky
generic
crovalimab-akkz
MOA
Complement C5 inhibitor
indication
Atypical Hemolytic Uremic Syndrome (Nondiarrhea - Associated Hemolytic Uremic Syndrome)
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 3m ago
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