pharmadog
News
when
  • Latest
  • Archive
by source
  • All Sources
  • Sources Page
Jobs
department
  • Clinical
  • Regulatory
  • Medical Affairs
  • Commercial
  • R&D / Discovery
  • Biostatistics / Data
  • Manufacturing / CMC
  • Market Access
therapeutic area
  • Oncology
  • Immunology
  • Neuroscience
  • Cardiovascular
  • Metabolic
  • Rare Disease
  • Infectious Disease
location & type
  • Remote Only
  • US Only
  • California
  • Massachusetts
  • Internships
  • Phase 3 Roles
  • All Jobs →
Sign InSubscribe
pharmadog

fetch the data · sniff the signal

Discover
  • Jobs
  • News
Hubs
  • Topics
  • Patent cliff
  • Publications
Tools
  • Compare
  • Search
  • Bookmarks
Trust
  • About
  • Sources
  • Contact
Legal
  • Privacy
  • Terms
  • Pricing

© 2026 pharmadog.xyz

made by humans and a good dog

  • home
  • jobs
  • news
  • search
  1. pharmadog
  2. ›drugs
  3. ›Unloxcyt
drug
save

cosibelimab

Marketedupdated 3mo ago
by Checkpoint Therapeutics Inc
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • drugUNLOXCYT8 co-mentions · 2 sources
  • tagApproval8 co-mentions · 2 sources
  • companyCheckpoint Therapeutics Inc4 co-mentions · 2 sources

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for head and neck squamous cell carcinoma and 2 investigational indications.

all catalysts(2)

approval · 2
Dec 13, 2024
approval
$CCCC
2y ago
UNLOXCYT (COSIBELIMAB-IPDL) — FDA approval
cosibelimab
→
Nov 21, 2025
approval
$CCCC
9mo ago
UNLOXCYT (COSIBELIMAB-IPDL) — FDA approval
cosibelimab
→

Trials studying cosibelimab

  • phase4Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancynot yet recruitingn=80
  • phase3Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLCterminatedn=25
  • phase1Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancersactive not recruitingn=272

News(0)

no news has mentioned this drug yet

brand
Unloxcyt
generic
cosibelimab-ipdl
MOA
12.1. Mechanism of Action PD-L1 may be expressed on tumor cells and tumor-infiltrating immune cells and can contribute to the inhibition of the anti-tumor immune response in the tumor microenvironment. Binding of PD-L1 to the PD-1 and B7.1 receptors found on T cells and antigen presenting cells suppresses cytotoxic T-cell activity, T-cell proliferation, and cytokine production. Cosibelimab-ipdl binds PD-L1 and blocks the interaction between PD-L1 and its receptors PD-1 and B7.1. This interaction releases the inhibitory effects of PD-L1 on the anti-tumor immune response. Cosibelimab-ipdl has also been shown to induce antibody-dependent cell-mediated cytotoxicity (ADCC) in vitro.
indication
Cutaneous Squamous Cell Carcinoma (cSCC)
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 25m ago
Found something off?
🐶 something off?

Report a data issue

Tell Bork what looks wrong — wrong sponsor, stale phase, mislinked ticker, anything. We’ll triage and fix.

comments(0)

5-min edit window · permanent after that
sign in to leave a comment · permanent archive after 5 minutes
no comments yet — first sniff?