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  1. pharmadog
  2. ›drugs
  3. ›CLEOCIN PHOSPHATE
drug · small molecule
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CLEOCIN PHOSPHATE

updated 3mo ago
/ /klɪndəˈmaɪsᵻn/ /
by $PFE PFIZER INC🔗 ChEMBL
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top 8
  • tagApproval684 co-mentions · 217 sources
  • drugCLEOCIN T595 co-mentions · 220 sources
  • drugCLEOCIN PHOSPHATE IN DEXTROSE 5% IN PLASTIC CONTAINER595 co-mentions · 220 sources
  • drugCLEOCIN595 co-mentions · 220 sources
  • drugCLEOCIN HYDROCHLORIDE430 co-mentions · 215 sources
  • drugclindamycin345 co-mentions · 220 sources
  • drugClindesse255 co-mentions · 130 sources
  • drugCLINDAMYCIN PHOSPHATE255 co-mentions · 130 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 17 approved and 3 investigational indications.

targets

Bacterial 70S ribosome

all catalysts(0)

nothing on the calendar yet

Trials studying CLEOCIN PHOSPHATE

  • phase4Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreonot yet recruitingn=100
  • —Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgarisactive not recruitingn=200
  • EP1Experience With Topical Acne Treatmentactive not recruitingn=72
  • phase1Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgariscompletedn=550
  • phase1A Study Comparing Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2% (Taro Pharmaceuticals U.S.A., Inc.) and CABTREO Topical Gel for the Treatment of Acne Vulgaris.completedn=382

News(0)

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brand
CLEOCIN PHOSPHATE
trade names
Cleocin, Cleocin phosphate, Cleocin t, Clinadac, Clinda-derm, Clindac
generic
CLINDAMYCIN PHOSPHATE
MOA
Mechanism of Action Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. Clindamycin is bacteriostatic.
indication
INDICATIONS AND USAGE CLEOCIN PHOSPHATE products are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. CLEOCIN PHOSPHATE products are also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate. Because of the risk of antibacterial drug-associated pseudomembranous colitis, as described in the BOXED WARNING , before selecting clindamycin the physician should consider the nature of the infection and the suitability of less toxic alternatives (e.g., erythromycin). Bacteriologic studies should be performed to determine the causative organisms and their susceptibility to clindamycin. Indicated surgical procedures should be performed in conjunction with antibacterial drug therapy. CLEOCIN PHOSPHATE is indicated in the treatment of serious infections caused by susceptible strains of the designated organisms in the conditions listed below: Lower respiratory tract infections including pneumonia, empyema, and lung abscess caused by anaerobes, Streptococcus pneumoniae, other streptococci (except E. faecalis ), and Staphylococcus aureus. Skin and skin structure infections caused by Streptococcus pyogenes, Staphylococcus aureus , and anaerobes. Gynecological infections including endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection caused by susceptible anaerobes. Intra-abdominal infections including peritonitis and intra-abdominal abscess caused by susceptible anaerobic organisms. Septicemia caused by Staphylococcus aureus , streptococci (except Enterococcus faecalis ), and susceptible anaerobes. Bone and joint infections including acute hematogenous osteomyelitis caused by Staphylococcus aureus and as adjunctive therapy in the surgical treatment of chronic bone and
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 11m ago
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