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  1. pharmadog
  2. ›drugs
  3. ›Zykadia
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ceritinib

Marketedupdated 3mo ago
by $NVS NOVARTIS AG
Approved
community read0 votes

🐶 often sniffed alongside

top 2
  • tagOncology2 co-mentions · 1 sources
  • companyBeijing Sanbo Brain Hospital1 co-mentions · 1 sources

indications

investigational
NSCLC

all catalysts(1)

phase 2 completion · 1
Apr 30, 2026
phase 2 completion
4mo ago
Beijing Sanbo Brain Hospital — ceritinib (Phase II Trial Completion)
ceritinib
→

Trials studying ceritinib

  • phase1Study of Safety and Efficacy of Ceritinib in Combination With Nivolumab in Patients With ALK-positive Non-small Cell Lung Canceractive not recruitingn=57
  • phase4Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Studyactive not recruitingn=233
  • —Managed Access Programs for LDK378, Ceritinibno longer available
  • phase1Next Generation Personalized Neuroblastoma Therapyterminatedn=66
  • phase1Study of Trametinib + Ceritinib in Patients With Unresectable Melanomacompletedn=27
  • phase2Pediatric Precision Laboratory Advanced Neuroblastoma Therapyrecruitingn=500
  • —A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.completedn=5,279
  • phase3LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinibcompletedn=231
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Nov 20, 2027
~1.3 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (15)

  • Dec 13, 2037method-of-use (U-3096)US 12357630
  • Feb 2, 2032method-of-use (U-1179)US 8703787
  • Feb 2, 2032method-of-use (U-1179)US 8703787
  • Jan 18, 2032compositionUS 9309229
  • Jan 18, 2032compositionUS 9309229
  • Jun 29, 2030compositionUS 80394793.9y
  • Jun 29, 2030compositionUS 80394793.9y
  • Apr 29, 2028compositionUS 79645921.7y
  • Apr 29, 2028compositionUS 79645921.7y
  • Nov 20, 2027method-of-use (U-1179)US 83779211.3y
  • Nov 20, 2027method-of-use (U-1179)US 83779211.3y
  • Nov 20, 2027compositionUS 83994501.3y
  • Nov 20, 2027compositionUS 83994501.3y
  • Apr 25, 2026compositionUS 7893074
  • Apr 25, 2026compositionUS 7893074

News(0)

no news has mentioned this drug yet

brand
Zykadia
generic
ceritinib
indication
Non-Small Cell Lung Cancer
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 15m ago
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