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  1. pharmadog
  2. ›drugs
  3. ›CARIPRAZINE HYDROCHLORIDE
drug · small molecule
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CARIPRAZINE HYDROCHLORIDE

Marketedupdated 3mo ago
by $ABBV AbbVie Inc.🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 4
  • tagApproval54 co-mentions · 14 sources
  • drugVRAYLAR53 co-mentions · 14 sources
  • tagSmall Molecule27 co-mentions · 14 sources
  • companyAurobindo Pharma Ltd1 co-mentions · 1 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for 3 indications.

indications

investigational
SchizophreniaMajor Depression

targets

D(2) dopamine receptorD(3) dopamine receptor

all catalysts(14)

approval · 14
Sep 17, 2015
approval
$ABBV250.09+0.85%
11y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Sep 17, 2015
approval
$ABBV250.09+0.85%
11y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Feb 23, 2017
approval
$ABBV250.09+0.85%
9y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Nov 9, 2017
approval
$ABBV250.09+0.85%
9y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Nov 9, 2017
approval
$ABBV250.09+0.85%
9y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Nov 28, 2018
approval
$ABBV250.09+0.85%
8y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
May 24, 2019
approval
$ABBV250.09+0.85%
7y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 16, 2022
approval
$ABBV250.09+0.85%
4y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Nov 22, 2024
approval
$ABBV250.09+0.85%
2y ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 16, 2025
approval
8mo ago
CARIPRAZINE HYDROCHLORIDE — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 18, 2025
approval
$ABBV250.09+0.85%
8mo ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 18, 2025
approval
$ABBV250.09+0.85%
8mo ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 18, 2025
approval
$ABBV250.09+0.85%
8mo ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
Dec 18, 2025
approval
$ABBV250.09+0.85%
8mo ago
VRAYLAR (CARIPRAZINE HYDROCHLORIDE) — FDA approval
CARIPRAZINE HYDROCHLORIDE
→
view all 14 catalysts →

Patent cliff

source: FDA Orange Book
first barrier falls
Dec 16, 2028
~2.3 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (50)

  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Mar 17, 2030patentUS 7737142*PED3.6y
  • Jan 16, 2030patentUS RE47350*PED3.4y
  • Jan 16, 2030patentUS RE47350*PED3.4y
  • Jan 16, 2030patentUS RE47350*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49110*PED3.4y
  • Jan 16, 2030patentUS RE49302*PED3.4y
  • Jan 16, 2030patentUS RE49302*PED3.4y
  • Jan 16, 2030patentUS RE49302*PED3.4y
  • Jan 16, 2030patentUS RE49302*PED3.4y
  • Sep 17, 2029compositionUS 77371423.1y
  • Sep 17, 2029compositionUS 77371423.1y
  • Sep 17, 2029compositionUS 77371423.1y
  • Sep 17, 2029compositionUS 77371423.1y
  • Sep 17, 2029compositionUS 77371423.1y
  • Sep 17, 2029compositionUS 77371423.1y
  • Jul 16, 2029method-of-use (U-2545)US RE473502.9y
  • Jul 16, 2029method-of-use (U-2544)US RE473502.9y
  • Jul 16, 2029method-of-use (U-2545)US RE473502.9y
  • Jul 16, 2029method-of-use (U-3503)US RE491102.9y
  • Jul 16, 2029method-of-use (U-2545)US RE491102.9y
  • Jul 16, 2029method-of-use (U-2543)US RE491102.9y
  • Jul 16, 2029method-of-use (U-3503)US RE491102.9y
  • Jul 16, 2029method-of-use (U-2544)US RE491102.9y
  • Jul 16, 2029method-of-use (U-3503)US RE491102.9y
  • Jul 16, 2029method-of-use (U-2545)US RE493022.9y
  • Jul 16, 2029method-of-use (U-3503)US RE493022.9y
  • Jul 16, 2029method-of-use (U-2545)US RE493022.9y
  • Jul 16, 2029method-of-use (U-3503)US RE493022.9y
  • Jun 20, 2029patentUS 7943621*PED2.9y
  • Jun 20, 2029patentUS 7943621*PED2.9y
  • Jun 16, 2029patentUS 7943621*PED2.8y
  • Jun 16, 2029patentUS 7943621*PED2.8y
  • Jun 16, 2029patentUS 7943621*PED2.8y
  • Jun 16, 2029patentUS 7943621*PED2.8y
  • Dec 20, 2028compositionUS 79436212.4y
  • Dec 20, 2028compositionUS 79436212.4y
  • Dec 16, 2028compositionUS 79436212.3y
  • Dec 16, 2028compositionUS 79436212.3y
  • Dec 16, 2028compositionUS 79436212.3y
  • Dec 16, 2028compositionUS 79436212.3y

FDA exclusivities (17)

  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Jun 18, 2029PEDPediatric (6mo bonus)2.9y
  • Dec 18, 2028NPPNew Product (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y
  • Dec 18, 2028NPPNew Product (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y
  • Dec 18, 2028NPPNew Product (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y
  • Dec 18, 2028NPPNew Product (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y
  • Dec 18, 2028NPPNew Product (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y
  • Dec 18, 2028M-14Method (3y)2.4y

News(2)

  • As BMS’ Cobenfy struggles to gain traction, MapLight knocks on the door
    Despite the recent emergence of a new drug class, schizophrenia remains one of the most challenging neuropsychiatric diseases to treat—and Cobenfy's first steps into the market indicate there is st…
    biospace · 2d ago
  • AbbVie shares pressured as Q2 I&I beat falls below investor expectations
    AbbVie investors’ sky-high expectations led to a 4% share decline on Friday as the company reported more modest consensus beats than expected.
    biospace · 11d ago
brand
CARIPRAZINE HYDROCHLORIDE
trade names
Reagila, Vraylar
generic
CARIPRAZINE HYDROCHLORIDE
MOA
Dopamine D2 receptor modulator; Dopamine D3 receptor modulator
indication
Autism Spectrum Disorder (ASD)
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 21m ago
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