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  1. pharmadog
  2. ›drugs
  3. ›camizestrant
drug · small molecule
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camizestrant

pre_registrationupdated 3mo ago
by $AZN ASTRAZENECA PLC🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 5
  • tagOncology3 co-mentions · 1 sources
  • tagBreast Cancer2 co-mentions · 1 sources
  • company$AZNASTRAZENECA PLC1 co-mentions · 1 sources
  • tagHER21 co-mentions · 1 sources
  • tagAdCom1 co-mentions · 1 sources

Small molecule drug with a maximum clinical stage of Phase 3 (across all indications), with 3 investigational indications.

targets

Estrogen receptor

all catalysts(1)

fda advisory committee meeting · 1
Apr 30, 2026
fda advisory committee meeting
$AZN158.75-1.95%
3mo ago
AstraZeneca Plc — camizestrant (FDA Advisory Committee Meeting)
camizestrant
→

Trials studying camizestrant

  • phase3An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)active not recruitingn=5,511
  • phase2Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancerrecruitingn=24
  • phase3Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancerrecruitingn=788
  • phase3A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapyrecruitingn=4,300
  • phase3A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancerrecruitingn=150
  • phase2A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumorsrecruitingn=564
  • phase2Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignanciesactive not recruitingn=702
  • phase1A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participantscompletedn=40
more trials →

News(8)

  • ‘Unlikely’ AstraZeneca-BMS mega-merger would be largest pharma deal ever
    If AstraZeneca and Bristol Myers Squibb were to successfully become one company, analysts say it could reset the current deal environment, which has picked up greatly in the first half of the year.
    biospace · 8d ago
  • Novo escalates legal fight with Lilly; J&J reinforces ‘dominance’ in multiple myeloma
    Novo is seeking an injunction that would halt allegedly “misleading” obesity drug ads. Elsewhere, the FDA began reviewing a highly anticipated medicine and a veteran investor landed at an AI startup.
    biopharma_dive · 18d ago
  • Wainua flop narrows AstraZeneca’s path to $80B goal ahead of high-risk readouts
    With a Phase 3 failure denting the rare disease drug’s prospects, AstraZeneca has little room for error as it plots a path toward its ambitious 2030 sales target.
    biospace · 20d ago
  • AstraZeneca's breast cancer PDUFA delayed; Arrowhead aims at same obesity target as Wave
    Plus news about Kailera, Alfasigma, Junshi and Kura. ⏰ FDA delays AstraZeneca’s camizestrant PDUFA date: The FDA has extended its PDUFA date for AstraZeneca’s breast cancer drug camizestrant, a few…
    endpoints · 2mo ago
  • Poll Results Highlight Breast Cancer Abstracts of Interest at ASCO 2026
    Readers share their opinions on some of the most talked-about breast cancer abstracts they’re looking forward to seeing at ASCO 2026.
    onclive · 3mo ago
  • ASCO 2026 HR+ and HER2+ Breast Cancer Preview: Read up on the Insights to Know Before You Go
    Breast cancer experts spotlight the abstracts they’re most excited to see at the 2026 ASCO Annual Meeting.
    onclive · 3mo ago
  • Summit’s ‘self-inflicted’ stumble; Esperion’s take-private deal
    Summit’s decision to conduct an interim analysis of a closely watched trial backfired. Elsewhere, Axsome got a much-needed label expansion and an FDA committee sided against an AstraZeneca breast c…
    biopharma_dive · 3mo ago
  • FDA's oncology advisors vote against 'new paradigm' in AstraZeneca trial
    In its first meeting in about nine months, the FDA’s advisory committee of oncology experts voted 6-3 Thursday that a late-stage trial for AstraZeneca’s oral SERD camizestrant didn't show a “clinic…
    endpoints · 3mo ago
generic
camizestrant
MOA
Estrogen receptor alpha degrader
indication
Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer)
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 26m ago
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