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  1. pharmadog
  2. ›drugs
  3. ›brexpiprazole LAI
drug · small molecule
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brexpiprazole LAI

Phase 1updated 3mo ago
by Bostal Drug Delivery Co Ltd🔗 ChEMBL
Phase 1
community read0 votes

🐶 often sniffed alongside

top 5
  • tagApproval12 co-mentions · 6 sources
  • drugBREXPIPRAZOLE7 co-mentions · 7 sources
  • tagSmall Molecule6 co-mentions · 6 sources
  • companyShanxi Ruifulai Pharmaceutical Co Ltd1 co-mentions · 1 sources
  • tagSchizophrenia1 co-mentions · 1 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 9 investigational indications.

targets

5-hydroxytryptamine receptor 2A5-hydroxytryptamine receptor 1AD(2) dopamine receptor

all catalysts(0)

nothing on the calendar yet

Trials studying brexpiprazole LAI

  • phase1Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescents With Schizophreniacompletedn=43
  • phase1Food Effect Study of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophreniacompletedn=59
  • phase3Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With Schizophreniacompletedn=295
  • phase1Bioequivalence Study to Compare Brexpiprazole 4 mg Film Coated Tablets Versus RXULTI 4 mg Film Coated Tablet (Brexpiprazole)completedn=36
  • phase1The Purpose of This Study is to Determine the Safety, Tolerability, and Pharmacokinetics of Brexpiprazole Long-acting Injection Following a Single Administration in Healthy Subjects/Patients With Schizophrenia.recruitingn=56
  • phase3Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disordercompletedn=119
  • —Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disordersrecruitingn=40
  • —REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)recruitingn=200
more trials →

News(0)

no news has mentioned this drug yet

trade names
Rexulti, Rxulti
generic
brexpiprazole
MOA
Serotonin 2a (5-HT2a) receptor antagonist; Serotonin 1a (5-HT1a) receptor partial agonist; Dopamine D2 receptor partial agonist
indication
Schizophrenia
phase
phase_1
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 52m ago
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