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  1. pharmadog
  2. ›drugs
  3. ›Adcetris
drug · antibody drug conjugate
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brentuximab vedotin

Phase 2updated 5mo ago
by $PFE PFIZER INC🔗 ChEMBL
Phase 2
community read0 votes

🐶 often sniffed alongside

top 2
  • companyKyowa Kirin Co Ltd1 co-mentions · 1 sources
  • tagOncology1 co-mentions · 1 sources

Antibody drug conjugate drug with a maximum clinical stage of Approval (across all indications), with 4 approved and 18 investigational indications.

indications

indications
DLBCL

targets

TubulinTumor necrosis factor receptor superfamily member 8

all catalysts(1)

phase 1 completion · 1
Apr 30, 2026
phase 1 completion
5mo ago
Kyowa Kirin Co Ltd — brentuximab vedotin (Phase I Trial Completion)
brentuximab vedotin
→

Trials studying brentuximab vedotin

  • phase2Brentuximab Vedotin and Lenalidomide in Treating Patients With Stage IB-IVB Relapsed or Refractory T-Cell Lymphomacompletedn=26
  • phase2Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphomacompletedn=45
  • phase2BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphomacompletedn=16
  • phase2Effectiveness of Concurrent Ultra-Low-Dose Total-Skin Electron Beam Therapy and Brentuximab Vedotin Given Quarterly Over 12 Months for Patients With Mycosis Fungoidesrecruitingn=30
  • phase3Brentuximab Vedotin in Early Stage Hodgkin Lymphomarecruitingn=1,042
  • phase2Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumorscompletedn=161
  • N/ABrentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphomacompletedn=118
  • phase2Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphomaactive not recruitingn=77

News(5)

  • Pfizer punts Seagen ADC, further muddying value of the $43B buyout
    The co-development deal comes after Pfizer reported a late-stage failure for a Seagen asset and the discontinuation of another investigational therapy developed by the company as a subsidiary of th…
    biospace · 1mo ago
  • Pfizer expands multibillion-dollar cost-cutting plan
    Hatched three years ago, the restructuring is now expected to deliver $1 billion in new cost reductions and save Pfizer another $1.5 billion by streamlining drug production.
    biopharma_dive · 2mo ago
  • Five Under 5: Top Oncology Videos for the Week of 5/3
    The top 5 OncLive TV videos of the week cover insights in ovarian cancer, classical Hodgkin lymphoma, pancreatic cancer, melanoma, and myelofibrosis.
    onclive · 4mo ago
  • UT MD Anderson Shares Latest Research Breakthroughs
    The University of Texas MD Anderson Cancer Center released recent oncology research highlights.
    onclive · 4mo ago
  • Dr Herrera on the Significance of the FDA Approval of Nivolumab Plus AVD for Classical Hodgkin Lymphoma
    Alex Herrera, MD, discusses the FDA approval of nivolumab plus AVD for classical Hodgkin lymphoma and its impact on clinical practice.
    onclive · 5mo ago
brand
Adcetris
trade names
Adcetris
generic
brentuximab vedotin
MOA
Tubulin inhibitor; Tumor necrosis factor receptor superfamily member 8 binding agent
indication
Angioimmunoblastic T-Cell Lymphoma (AITL)/Immunoblastic Lymphadenopathy
phase
phase_2
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 42m ago
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