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  1. pharmadog
  2. ›drugs
  3. ›Yescarta
drug · gene
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axicabtagene ciloleucel

Phase 3updated 3mo ago
by $GILD GILEAD SCIENCES, INC.🔗 ChEMBL
Phase 3
community read0 votes

Gene drug with a maximum clinical stage of Approval (across all indications), with an approval for follicular lymphoma and diffuse large b-cell lymphoma and 5 investigational indications.

indications

indications
DLBCL

targets

B-lymphocyte antigen CD19

all catalysts(0)

nothing on the calendar yet

Trials studying axicabtagene ciloleucel

  • phase3A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapyrecruitingn=400
  • phase3Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapyrecruitingn=550
  • phase3Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphomaactive not recruitingn=300
  • phase2Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 1 and Cohort 2)completedn=105
  • —Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cellsenrolling by invitationn=1,000
  • phase2Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphomarecruitingn=396
  • phase2Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphomacompletedn=35
  • phase2A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphomacompletedn=159
more trials →

News(3)

  • Lilly, AbbVie climb aboard in vivo CAR T train—but safety remains a hurdle
    Safety will be the key determinant of in vivo CAR T therapies, according to H.C. Wainwright’s Mitchel Kapoor, who noted that convenience and efficacy won’t be enough to impress investors in this sp…
    biospace · 19d ago
  • Study of Yescarta patients reveals genetic red flags for CAR-T therapy side effects
    A new analysis of patients who took part in clinical trials for Kite Pharma’s CAR-T cell therapy Yescarta has revealed genetic signatures of toxicity risk, potentially providing a path forward for…
    fiercebiotech · 21d ago
  • Repligen strikes $1.5B BioLife buyout to bag cell therapy product pharmas rely on
    Top-selling cell therapies from BMS, J&J and Gilead depend on a BioLife product, positioning Repligen to use the takeover to increase its exposure to the modality.
    biospace · 23d ago
brand
Yescarta
trade names
Yescarta
generic
axicabtagene ciloleucel
MOA
B-lymphocyte antigen CD19 binding agent
indication
Diffuse Large B-Cell Lymphoma
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 31m ago
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