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  1. pharmadog
  2. ›drugs
  3. ›Erleada
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apalutamide

Marketedupdated 3mo ago
by $JNJ JOHNSON & JOHNSON
Approved
community read0 votes

🐶 often sniffed alongside

top 4
  • drugERLEADA60 co-mentions · 15 sources
  • tagApproval60 co-mentions · 15 sources
  • companyJanssen Biotech Inc30 co-mentions · 15 sources
  • tagSmall Molecule30 co-mentions · 15 sources

indications

investigational
Prostate Cancer

all catalysts(15)

approval · 15
Feb 14, 2018
approval
9y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Sep 17, 2019
approval
7y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Jul 10, 2020
approval
6y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Sep 1, 2020
approval
6y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Nov 20, 2020
approval
6y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Jul 14, 2021
approval
5y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Sep 7, 2021
approval
5y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Apr 26, 2022
approval
4y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Nov 8, 2022
approval
4y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Nov 8, 2022
approval
4y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Feb 17, 2023
approval
4y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Dec 19, 2023
approval
3y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Jul 9, 2024
approval
2y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Aug 2, 2024
approval
2y ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
Mar 5, 2026
approval
6mo ago
ERLEADA (APALUTAMIDE) — FDA approval
apalutamide
→
view all 15 catalysts →

Trials studying apalutamide

  • phase2Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancerrecruitingn=315
  • phase3A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomyactive not recruitingn=2,517
  • phase2Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Canceractive not recruitingn=7
  • phase3An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLASactive not recruitingn=1,503
  • phase1A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Canceractive not recruitingn=19
  • phase2Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.recruitingn=192
  • phase3An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)active not recruitingn=982
  • phase3A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Canceractive not recruitingn=1,207
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Mar 27, 2027
218 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (28)

  • Jan 14, 2041method-of-use (U-4449)US 11723898
  • Jan 14, 2041method-of-use (U-4449)US 11723898
  • Jan 30, 2040method-of-use (U-3901)US 11963952
  • Jan 30, 2040method-of-use (U-3901)US 11963952
  • Jan 30, 2040method-of-use (U-4201)US 12303497
  • Jan 30, 2040method-of-use (U-4201)US 12303497
  • Apr 30, 2038method-of-use (U-3012)US 10702508
  • Apr 30, 2038method-of-use (U-3012)US 10702508
  • Dec 3, 2035formulationUS 12303493
  • Dec 3, 2035formulationUS 12303493
  • Sep 23, 2033method-of-use (U-3013)US 10849888
  • Sep 23, 2033method-of-use (U-3013)US 10849888
  • Sep 23, 2033method-of-use (U-2237)US 9884054
  • Sep 23, 2033method-of-use (U-2237)US 9884054
  • Sep 23, 2033method-of-use (U-2381)US RE49353
  • Sep 23, 2033method-of-use (U-2381)US RE49353
  • Sep 23, 2033method-of-use (U-4450)US RE50642
  • Sep 23, 2033method-of-use (U-4450)US RE50642
  • Jun 4, 2033compositionUS 9481663
  • Jun 4, 2033compositionUS 9481663
  • Sep 15, 2030compositionUS 84455074.1y
  • Sep 15, 2030compositionUS 84455074.1y
  • Mar 27, 2027method-of-use (U-2624)US 8802689218d
  • Mar 27, 2027method-of-use (U-2624)US 8802689218d
  • Mar 27, 2027compositionUS 9388159218d
  • Mar 27, 2027compositionUS 9388159218d
  • Mar 27, 2027formulationUS 9987261218d
  • Mar 27, 2027formulationUS 9987261218d

News(3)

  • J&J dips despite upbeat outlook; AstraZeneca, Spero cut China deals
    J&J’s shares ticked down as oncology sales missed expectations. Elsewhere, AstraZeneca bet $600 million on a lung cancer drug and a pair of biotechs snagged two of the year’s top venture rounds.
    biopharma_dive · 1mo ago
  • #ASCO26: Erleada succeeds in early-stage prostate cancer study, but questions remain
    CHICAGO — As part of a hormone therapy regimen for prostate cancer, J&J’s Erleada cut the risk of metastasis or death by 20% when given around surgery, researchers reported Sunday. Treatment with t…
    endpoints · 2mo ago
  • GU Cancer Experts Highlight Top Abstracts to Watch During ASCO 2026
    We spoke with leading voices in GU oncology to see which presentations they are most looking forward to during the 2026 ASCO Annual Meeting.
    onclive · 3mo ago
brand
Erleada
generic
apalutamide [INN]
indication
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 35m ago
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