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  1. pharmadog
  2. ›drugs
  3. ›Saphnelo
drug · antibody
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anifrolumab

Phase 3updated 5mo ago
by $AZN ASTRAZENECA PLC🔗 ChEMBL
Phase 3
community read0 votes

Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for systemic lupus erythematosus and 7 investigational indications.

indications

indications
Lupus

targets

Interferon alpha/beta receptor 1

all catalysts(0)

nothing on the calendar yet

Trials studying anifrolumab

  • phase4Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Usersrecruitingn=16
  • phase3Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)active not recruitingn=314
  • —The Anifrolumab PRIM Programrecruitingn=240
  • phase3A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosusrecruitingn=245
  • phase3An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participantsrecruitingn=100
  • phase2A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosusnot yet recruitingn=24
  • —Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.recruitingn=218
  • —Anifrolumab Malignancy and Serious Infections Studyrecruitingn=3,195

News(2)

  • Beeline flies into phase 3 as oral lupus drug soars past placebo
    A phase 2 trial of Beeline Medicines’ afimetoran has hit its primary endpoint, positioning the biotech to swarm into pivotal development in two forms of lupus.
    fiercebiotech · 20d ago
  • 10 clinical trials to watch in the second half of 2026
    The biotechnology sector’s upswing accelerated in the first half. Positive results from anticipated trials in lung cancer, Alzheimer’s and multiple autoimmune conditions could add to the momentum.
    biopharma_dive · 3mo ago
brand
Saphnelo
trade names
Saphnelo
generic
anifrolumab-fnia
MOA
Interferon-alpha/beta receptor alpha chain antagonist
indication
Idiopathic Inflammatory Myopathy (IIM)
phase
phase_3
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 1h ago
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