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  1. pharmadog
  2. ›drugs
  3. ›Voquezna Dual Pak
drug
save

amoxicillin + vonoprazan fumarate

Marketedupdated 3mo ago
by $PHAT Phathom Pharmaceuticals, Inc.
Approved
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval12 co-mentions · 6 sources
  • drugVOQUEZNA DUAL PAK12 co-mentions · 6 sources
  • tagSmall Molecule6 co-mentions · 6 sources
  • drugVOQUEZNA6 co-mentions · 6 sources
  • drugVOQUEZNA TRIPLE PAK6 co-mentions · 6 sources
  • drugvonoprazan fumarate6 co-mentions · 6 sources
  • drugamoxicillin6 co-mentions · 6 sources
  • drugLarotid6 co-mentions · 6 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 11 approved and 49 investigational indications.

all catalysts(6)

approval · 6
May 3, 2022
approval
$PHAT9.2800-3.13%
4y ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→
Aug 16, 2023
approval
$PHAT9.2800-3.13%
3y ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→
May 1, 2024
approval
$PHAT9.2800-3.13%
2y ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→
Jul 31, 2024
approval
$PHAT9.2800-3.13%
2y ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→
Jun 12, 2025
approval
$PHAT9.2800-3.13%
1y ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→
Oct 31, 2025
approval
$PHAT9.2800-3.13%
10mo ago
VOQUEZNA DUAL PAK (AMOXICILLIN) — FDA approval
amoxicillin + vonoprazan fumarate
→

Patent cliff

source: FDA Orange Book
first barrier falls
May 3, 2027
258 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Aug 11, 2030formulationUS 91864114.0y
  • Apr 10, 2030compositionUS 79774883.6y

FDA exclusivities (2)

  • May 3, 2032GAINGAIN Antibiotic (5y)
  • May 3, 2027NCENew Chemical Entity (5y)258d

News(0)

no news has mentioned this drug yet

brand
Voquezna Dual Pak
generic
amoxicillin + vonoprazan fumarate
MOA
12.1 Mechanism of Action Vonoprazan suppresses basal and stimulated gastric acid secretion at the secretory surface of the gastric parietal cell through inhibition of the H + , K + -ATPase enzyme system in a potassium competitive manner. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, vonoprazan has been characterized as a type of gastric proton-pump inhibitor, in that it blocks the final step of acid production. Vonoprazan does not require activation by acid. Vonoprazan may selectively concentrate in the parietal cells in both the resting and stimulated states. Vonoprazan binds to the active proton pumps in a noncovalent and reversible manner. Amoxicillin is an antibacterial drug. Clarithromycin is a macrolide antimicrobial drug [see Microbiology (12.4) ]. Acid suppression enhances the replication of H. pylori bacteria and the stability and effectiveness of antimicrobials in the treatment of H. pylori infection.
indication
Helicobacter pylori Infections
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 30m ago
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