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  3. ›Gocovri
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amantadine hydrochloride ER

Marketedupdated 2mo ago
by Adamas Pharmaceuticals Inc
Approved
community read0 votes

🐶 often sniffed alongside

top 3
  • tagApproval4 co-mentions · 2 sources
  • tagSmall Molecule2 co-mentions · 2 sources
  • drugamantadine hydrochloride2 co-mentions · 2 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 3 investigational indications.

indications

investigational
Parkinson's Disease

all catalysts(0)

nothing on the calendar yet

Trials studying amantadine hydrochloride ER

  • phase2Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).active not recruitingn=45
  • phase4Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Diseasecompletedn=8
  • phase2Urinary Excretion of Acetylamantadine by Cancer Patientscompletedn=150

Patent cliff

source: FDA Orange Book
first barrier falls
Jan 22, 2028
~1.5 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (60)

  • Aug 23, 2038formulationUS 11065213
  • Aug 23, 2038formulationUS 11065213
  • Aug 23, 2038method-of-use (U-2106)US 11077073
  • Aug 23, 2038method-of-use (U-3180)US 11077073
  • Aug 23, 2038method-of-use (U-3180)US 12233033
  • Aug 23, 2038method-of-use (U-2224)US 12233033
  • Feb 15, 2038method-of-use (U-20)US 10213393
  • Feb 15, 2038method-of-use (U-20)US 10213393
  • Feb 15, 2038method-of-use (U-20)US 10213393
  • Feb 15, 2038method-of-use (U-20)US 10213393
  • Feb 15, 2038method-of-use (U-2497)US 10213394
  • Feb 15, 2038method-of-use (U-2497)US 10213394
  • Feb 15, 2038method-of-use (U-2497)US 10213394
  • Feb 15, 2038method-of-use (U-2497)US 10213394
  • Feb 15, 2038method-of-use (U-20)US 10500170
  • Feb 15, 2038method-of-use (U-20)US 10500170
  • Feb 15, 2038method-of-use (U-20)US 10500170
  • Feb 15, 2038method-of-use (U-20)US 10500170
  • Feb 15, 2038method-of-use (U-2497)US 10500171
  • Feb 15, 2038method-of-use (U-2497)US 10500171
  • Feb 15, 2038method-of-use (U-2497)US 10500171
  • Feb 15, 2038method-of-use (U-2497)US 10500171
  • Feb 15, 2038method-of-use (U-2497)US 10500172
  • Feb 15, 2038method-of-use (U-2497)US 10500172
  • Feb 15, 2038method-of-use (U-2497)US 10500172
  • Feb 15, 2038method-of-use (U-2497)US 10500172
  • Feb 15, 2038method-of-use (U-2497)US 10512617
  • Feb 15, 2038method-of-use (U-2497)US 10512617
  • Feb 15, 2038method-of-use (U-2497)US 10512617
  • Feb 15, 2038method-of-use (U-2497)US 10512617
  • Feb 15, 2038method-of-use (U-2497)US 11890261
  • Feb 15, 2038method-of-use (U-2497)US 11890261
  • Dec 4, 2034method-of-use (U-2459)US 10154971
  • Dec 4, 2034method-of-use (U-2459)US 10154971
  • Jun 17, 2034method-of-use (U-2808)US 10646456
  • Jun 17, 2034method-of-use (U-2808)US 10646456
  • Jun 17, 2034method-of-use (U-3822)US 11903908
  • Jun 17, 2034method-of-use (U-3822)US 11903908
  • Dec 2, 2030method-of-use (U-2106)US 111978354.4y
  • Dec 2, 2030method-of-use (U-2106)US 111978354.4y
  • Dec 2, 2030method-of-use (U-2106)US 87413434.4y
  • Dec 2, 2030method-of-use (U-2106)US 87413434.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677914.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677914.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677924.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677924.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677934.4y
  • Dec 2, 2030method-of-use (U-2106)US 98677934.4y
  • Dec 2, 2030method-of-use (U-2224)US 98779334.4y
  • Dec 2, 2030method-of-use (U-2224)US 98779334.4y
  • Mar 13, 2030formulationUS 82523313.6y
  • Mar 13, 2030formulationUS 82523313.6y
  • Mar 13, 2030formulationUS 82523313.6y
  • Mar 13, 2030formulationUS 82523313.6y
  • Jan 22, 2028method-of-use (U-2105)US 83895781.5y
  • Jan 22, 2028method-of-use (U-219)US 83895781.5y
  • Jan 22, 2028method-of-use (U-2105)US 83895781.5y
  • Jan 22, 2028method-of-use (U-3054)US 83895781.5y
  • Jan 22, 2028method-of-use (U-3054)US 83895781.5y
  • Jan 22, 2028method-of-use (U-219)US 83895781.5y

News(0)

no news has mentioned this drug yet

brand
Gocovri
generic
amantadine hydrochloride
MOA
Matrix protein 2 inhibitor; Glutamate [NMDA] receptor antagonist
indication
Dyskinesia
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 1h ago
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