drug
acetaminophen ER
Marketedupdated 5mo agoby Granules USA Inc
Approvedcommunity read0 votes
Small molecule drug with a maximum clinical stage of Approval (across all indications), with 18 approved and 81 investigational indications.
all catalysts(100)
approval · 100
Jun 20, 1978
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 25, 1980
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 21, 1981
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 29, 1982
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 1, 1982
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 3, 1982
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 16, 1982
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 7, 1983
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 29, 1984
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 10, 1984
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 10, 1984
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 21, 1985
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 26, 1985
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 13, 1986
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 20, 1986
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 18, 1986
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 18, 1986
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Oct 23, 1986
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 3, 1986
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 19, 1986
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 5, 1987
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 18, 1988
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 11, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jun 9, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 1, 1988
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 1, 1988
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 7, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 30, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 30, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 30, 1988
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Oct 21, 1988
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Oct 21, 1988
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Oct 21, 1988
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 8, 1989
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 8, 1989
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 15, 1989
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 15, 1989
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 15, 1989
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 16, 1989
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 29, 1989
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 28, 1989
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 18, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 18, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 18, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 14, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 14, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Nov 8, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Nov 8, 1990
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 1, 1991
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 1, 1991
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 1, 1991
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Apr 3, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 9, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 29, 1991
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 29, 1991
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 8, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 16, 1991
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 18, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 18, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 18, 1991
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Apr 6, 1992
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jun 19, 1992
approval
OXYCET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 16, 1992
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 16, 1992
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Oct 27, 1992
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 4, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 29, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
May 13, 1993
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 16, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 16, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 17, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 23, 1993
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 2, 1993
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jan 24, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jan 24, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 16, 1994
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 19, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 24, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 15, 1994
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 22, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 28, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 28, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 28, 1994
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 16, 1995
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 16, 1995
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Mar 16, 1995
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jun 19, 1995
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 1, 1995
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Sep 22, 1995
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Dec 8, 1995
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Feb 12, 1996
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Apr 26, 1996
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 28, 1996
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 28, 1996
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 28, 1996
approval
ROXICET (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Aug 28, 1996
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Apr 8, 1997
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Apr 8, 1997
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 8, 1997
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Jul 8, 1997
approval
ACETAMINOPHEN AND CODEINE PHOSPHATE (ACETAMINOPHEN) — FDA approval
acetaminophen ER
→
Trials studying acetaminophen ER
- phase3A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
- phase1A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
- phase3A Study of Combogesic® IV (Intravenous) in Pediatric Patients With Acute Pain
- phase3A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
- phase3Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
- phase2A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
- phase3A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
- phase3SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
Patent cliff
source: FDA Orange Bookfirst barrier falls
Oct 17, 2026
12 days
Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.
patents (43)
- Jul 9, 2041formulationUS 11918693
- Jan 14, 2036formulationUS 11213498
- Jul 17, 2035formulationUS 11389416
- Jul 17, 2035method-of-use (U-3745)US 12083087
- May 16, 2032formulationUS 8658631
- May 16, 2032formulationUS 8741885
- May 16, 2032formulationUS 8992975
- May 16, 2032formulationUS 9050335
- May 16, 2032method-of-use (U-1499)US 9468636
- Mar 11, 2032patentUS 9399012*PED
- Oct 26, 2031method-of-use (U-3745)US 11446266
- Oct 26, 2031method-of-use (U-3745)US 11896567
- Oct 26, 2031method-of-use (U-4307)US 12220392
- Sep 11, 2031method-of-use (U-2261)US 93990124.9y
- Feb 22, 2031compositionUS 84611374.4y
- Feb 22, 2031compositionUS 84611374.4y
- Feb 22, 2031compositionUS 84611374.4y
- Dec 21, 2030formulationUS 85976814.2y
- Dec 21, 2030formulationUS 89803194.2y
- Jul 1, 2030compositionUS 87484133.7y
- Jul 1, 2030compositionUS 87484133.7y
- Jul 1, 2030compositionUS 87484133.7y
- Jul 1, 2030formulationUS 88289783.7y
- Jul 1, 2030formulationUS 88289783.7y
- Jul 1, 2030formulationUS 88289783.7y
- Jul 1, 2030compositionUS 91321253.7y
- Jul 1, 2030compositionUS 91321253.7y
- Jul 1, 2030compositionUS 91321253.7y
- Jul 1, 2030compositionUS 95499233.7y
- Jul 1, 2030compositionUS 95499233.7y
- Jul 1, 2030compositionUS 95499233.7y
- Apr 19, 2030formulationUS 87419593.5y
- Nov 19, 2029formulationUS 83774533.1y
- May 13, 2029patentUS 10383834*PED2.6y
- May 13, 2029patentUS 9610265*PED2.6y
- May 13, 2029patentUS 9987238*PED2.6y
- Mar 11, 2029formulationUS 83724322.4y
- Mar 11, 2029formulationUS 83944082.4y
- Mar 11, 2029method-of-use (U-1499)US 86689292.4y
- Nov 13, 2028method-of-use (U-2621)US 103838342.1y
- Nov 13, 2028method-of-use (U-2263)US 96102652.1y
- Nov 13, 2028method-of-use (U-2261)US 99872382.1y
- Jun 1, 2027method-of-use (U-1498)US 7976870239d
FDA exclusivities (2)
- Oct 17, 2026NPNP12d
- Jan 7, 2026PCPC
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