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PUBLIC COMPANY
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$SLNSilence Therapeutics plc

$SLN
London, GBupdated 18d ago

Silence Therapeutics is a London-based pharmaceutical company formed in 1994. The company has pioneered the development of short-interfering ribonucleic acid (siRNA) therapeutics for the treatment of rare diseases. Silence Therapeutics has offices in London, New Jersey, and Berlin, with its corporate headquarters located in Hammersmith, London.

Website ↗SEC EDGAR ↗Yahoo Finance ↗
community read0 votes
pipeline
2
marketed
0
phase 3
0
catalysts ytd
0
approvals ytd
0
recalls ytd
0

Pipeline(2)

pipeline depth2 products
Phase 2: 2
2Phase 2
Phase 2
divesiran
Polycythemia Vera
Phase 2
zerlasiran sodium
Atherosclerosis

📅 Upcoming

no upcoming catalysts on record

🕒 Recent(90d)

nothing in the last 90 days
view all catalysts →

Active trials

  • phase2Study to Assess SLN124 in Patients With Polycythemia Veraactive not recruitingn=69
  • phase2Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Eventscompletedn=180
  • phase1Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)completedn=70
  • phase1A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndromecompletedn=44
🐶 Hiring Signal
No open roles indexed yet — view Silence Therapeutics plc jobs →

News

  • Silence cashes in on ‘differentiated’ data; UK reaffirms support for childhood vaccines
    Some analysts believe Silence’s polycythemia vera drug could be superior to a closely watched Takeda medicine. Elsewhere, the FDA spurned a radiopharmaceutical and AbCellera shares climbed to level…
    biopharma_dive · 5d ago
  • Silence causes uproar in rare blood cancer space as data sets high bar for competitors
    The mid-stage win of Silence Therapeutics’ siRNA drug in polycythemia vera validates the therapeutic approach of similar assets in development—but also sets a high standard for therapies from Taked…
    biospace · 6d ago
  • STAT+: In surprise decision, FDA rejects radiopharma therapy expected to rival Novartis treatment
    The FDA has rejected a radiopharmaceutical therapy because of manufacturing issues, halting what would have been a competitor for Novartis.
    stat · 7d ago
  • STAT+: FDA panel to weigh Grail’s Galleri test
    China reins in its biotech innovation engine, radiopharma boom meets unexpected hurdles, and more news from The Readout
    stat · 7d ago
  • STAT+: Sionna’s experimental cystic fibrosis pill falls flat in mid-stage trial
    A pill from Sionna Therapeutics provided no added benefit when combined with Vertex's cystic fibrosis blockbuster Trikafta, a blow to the biotech.
    stat · 7d ago
  • STAT+: Heart failure drug from Tenax Therapeutics fails in pivotal study
    A Tenax Therapeutics drug designed to treat a type of heart failure associated with high blood pressure in the lungs failed in a closely watched study.
    stat · 7d ago
  • Silence spells out Phase 2 success for gene-silencing drug in rare blood cancer
    Silence Therapeutics is set to advance its siRNA drug for the rare blood disorder polycythemia vera (PV) into Phase 3 following a successful mid-stage trial. Silence said Monday that its drug ...
    endpoints · 7d ago
  • STAT+: Silence Therapeutics aims at Takeda with new data in rare blood cancer
    A rare blood cancer drug from Silence Therapeutics showed strong results in a trial, potentially setting it up to compete with a Takeda medicine.
    stat · 7d ago
  • Silence brings the noise to Takeda with phase 2 blood cancer win
    A phase 2 trial of Silence Therapeutics’ divesiran has hit its primary endpoint, emboldening the biotech to gear up for late-phase development of a potential challenger to Takeda and Protagonist Th…
    fiercebiotech · 8d ago
view all news mentions →
identifiers
ticker
$SLN
SEC CIK
0001479615
country
GB
source
sec_tickers
top tags
Cardiology1Oncology1
mentioned in
9news items
entity-linker matched
Data sources
SEC EDGAR
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