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4,686 catalysts · 18,987 approval · 5,000 device 510k · 4,728 grant · 4,686 phase readout · 2,347 8k filing · 2,000 device pma

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  • approval18,987
  • device 510k5,000
  • grant4,728
  • phase readout4,686
  • 8k filing2,347
  • device pma2,000
  • device recall
2,000
  • recall1,126
  • device adverse event1,000
  • earnings292
  • therapy area

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    Date TBD

    50
    ›RECRUITINGphase readoutNCT07483047: Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study

    Sponsor: Shanghai Geriatric Medical Center. Phase: . Conditions: Postoperative Cognitive Dysfunction (POCD), Cardiac Diseases Requiring Surgery

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT03065452: Sagittal Imbalance and Lumbar Stenosis Surgery: Decompression Without Implant

    Sponsor: Centre Hospitalier Universitaire Dijon. Phase: . Conditions: Lumbar Stenosis, Familial

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07401849: Blood Biomarkers for Early and Accurate Diagnosis of Alzheimer's Disease in Primary Care

    Sponsor: Imperial College London. Phase: . Conditions: Alzheimer Disease, Biomarkers / Blood, Biomarker in Early Diagnosis, Mild Cognitive Impairment (MCI)

    full page →ctgov ↗
    ›ENROLLING_BY_INVITATIONphase readoutNCT07564947: Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease (GL-MAFLD-NRF2 Study)

    Sponsor: University of Agriculture, Peshawar. Phase: NA. Conditions: MAFLD, Fatty Liver, Fatty Liver, Non-alcoholic Fatty Liver Disease, NAFLD, Fatty Liver, Nonalcoholic, Fatty Liver Disease, Oxidative Stress, Inflammation

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT00983658: A Study of huMAb OX40L in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic Asthma

    Sponsor: Genentech, Inc.. Phase: PHASE2. Conditions: Asthma

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06607458: Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

    Sponsor: Delcath Systems Inc.. Phase: PHASE2. Conditions: Refractory Metastatic Colorectal Cancer

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06839248: Effect of Fasting Recommendations Among Patients Using GLP-1 Receptor Agonists

    Sponsor: St Vincent's Hospital Melbourne. Phase: NA. Conditions: Residual Gastric Contents, Pulmonary Aspiration of Gastric Contents

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07478848: Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

    Sponsor: Abramson Cancer Center at Penn Medicine. Phase: PHASE1. Conditions: Large B Cell Lymphoma, Non Hodgkin Lymphoma (NHL), Diffuse Large B Cell Lymphoma (DLBCL), Diffuse Large B Cell Lymphoma Refractory, Diffuse Large B Cell Lymphoma Relapsed

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07242248: A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)

    Sponsor: Janssen-Cilag Ltd.. Phase: . Conditions: Inflammatory Bowel Disease, Colitis, Ulcerative, Crohn's Disease

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07180355: A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

    Sponsor: Solid Biosciences Inc.. Phase: PHASE1. Conditions: Friedreich's Ataxia (FA)

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT06747455: BCG for Therapeutic Use Phase Ⅲ Clinical Trial

    Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.. Phase: PHASE3. Conditions: BCG

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07634055: Assessment of Motor Reserve in the Preclinical Stages of Dementia

    Sponsor: Istituto per la Ricerca e l'Innovazione Biomedica. Phase: . Conditions: Mild Cognitive Impairment (MCI)

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT07405957: Effects of Two Different Lion's Mane Extracts (Lions Mane Fruiting Body & Lions Mane Fruiting Body With Mycellium) on Cognitive Performance, Subjective Affect, Serum Biomarkers, and Gut Microbiota in Healthy Adults

    Sponsor: Applied Food Sciences Inc.. Phase: NA. Conditions: Healthy Adult Females, Healthy Adult Male

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06771401: Identification of Biomarkers in Cervical Mucus

    Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Phase: NA. Conditions: Cervical Mucus Dysfunction, Infertility, Female

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06393712: A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

    Sponsor: Alnylam Pharmaceuticals. Phase: PHASE2. Conditions: Cerebral Amyloid Angiopathy

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT06712719: Effects of Dietary Phosphorus on Phosphorus and Calcium Whole-Body Balance and Kinetics in Moderate CKD

    Sponsor: University of Minnesota. Phase: NA. Conditions: CKD

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT05675930: A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

    Sponsor: Memorial Sloan Kettering Cancer Center. Phase: PHASE2. Conditions: Graft-Versus-Host Disease, GVHD, Undefined

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT07401667: Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla.

    Sponsor: Dr R Viswa Chandra. Phase: NA. Conditions: Papilla Reconstruction

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06669000: Time Required to Dissolve Urate Deposits

    Sponsor: Assistance Publique - Hôpitaux de Paris. Phase: . Conditions: Gout

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT03171311: The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

    Sponsor: Aarhus University Hospital Skejby. Phase: NA. Conditions: Ischaemic Heart Disease, Ischemic Heart Disease

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07361471: Identification of Genetic, Phenotypic, Clinical, Biological and Histological Factors Differentiating Patients With Ovarian Cancer Who Are Refractory to Platinum-based Therapy From Patients Defined as Long-term Responders to Platinum-based Therapy

    Sponsor: Centre Jean Perrin. Phase: NA. Conditions: Ovarian Cancer

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT05618444: Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA

    Sponsor: Geisinger Clinic. Phase: NA. Conditions: Obstructive Sleep Apnea

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06488144: Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

    Sponsor: VA Office of Research and Development. Phase: PHASE3. Conditions: Osteoarthritis, Knee

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07432334: CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus

    Sponsor: Vinmec Research Institute of Stem Cell and Gene Technology. Phase: PHASE1. Conditions: Refractory Systemic Lupus Erythematosus

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT07164664: External Oblique Intercostal Block in Laparoscopic Cholecystectomy

    Sponsor: Ondokuz Mayıs University. Phase: NA. Conditions: Pain, Postoperative, Pain, Acute, Opioid Use

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT03805464: Walking Gait Biomechanics Following Knee Joint Effusion

    Sponsor: Duke University. Phase: NA. Conditions: Knee Injuries, Knee Osteoarthritis

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT07504809: Research on the Effectiveness of Remote Rehabilitation l for Shoulder and Neck Recovery in Oral Cancer Patients After Selective Neck Dissection

    Sponsor: Pai Pang. Phase: NA. Conditions: Oral Cancer Patients After Selective Neck Dissection

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT07630909: Mesotherapy for the Management of Myofascial Pain Syndrome

    Sponsor: Future University in Egypt. Phase: NA. Conditions: Myofascial Pain Syndrome (MPS)

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06413498: A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

    Sponsor: Kite, A Gilead Company. Phase: PHASE3. Conditions: Multiple Myeloma

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT04163198: Optimisation of Mechanical Insufflation:Exsufflation

    Sponsor: Guy's and St Thomas' NHS Foundation Trust. Phase: NA. Conditions: Neuromuscular Diseases

    full page →ctgov ↗
    ›SUSPENDEDphase readoutNCT06213298: Effect of Kava on Anxiety and Stress in Cancer Survivors

    Sponsor: Masonic Cancer Center, University of Minnesota. Phase: EARLY_PHASE1. Conditions: Kava, Anxiety, Stress, Cancer, Depression, Sleep

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT06131398: A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

    Sponsor: Amgen. Phase: PHASE1. Conditions: Advanced Solid Tumors

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT06412198: A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

    Sponsor: M.D. Anderson Cancer Center. Phase: PHASE1. Conditions: Metastatic Colorectal Cancer, KRAS G12C Mutations

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT05689463: Evaluation of the Prevalence of BP180 and BP230 Autoantibodies in the Serum of Patients With Pruritus Under Immunotherapy

    Sponsor: University Hospital, Rouen. Phase: NA. Conditions: Patients With Chronic Pruritus for More Than 1 Month Who Have Received Immunotherapy

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07246863: Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

    Sponsor: CatalYm GmbH. Phase: PHASE2. Conditions: Metastatic Non-Squamous Non-Small Cell Lung Cancer, Adult Solid Tumor

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT05501093: Diabetes Reversal and the Subgingival Microbiota

    Sponsor: University of Pennsylvania. Phase: . Conditions: Diabetes type2, Bariatric Surgery Candidate

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07590193: A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus

    Sponsor: Amgen. Phase: PHASE1. Conditions: Diabetes Mellitus, Type 2

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT04211714: Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure

    Sponsor: Elixirgen Therapeutics, Inc.. Phase: PHASE1. Conditions: Telomere Shortening, Bone Marrow Failure

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07400016: Efficacy of Superoxide Dismutase Spray in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .

    Sponsor: West China Hospital. Phase: NA. Conditions: Radiation Dermatitis

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT04889716: CAR-T Followed by Bispecific Antibodies

    Sponsor: Abramson Cancer Center at Penn Medicine. Phase: PHASE2. Conditions: Large B-cell Lymphoma, DLBCL - Diffuse Large B Cell Lymphoma

    full page →ctgov ↗
    ›TERMINATEDphase readoutNCT04347616: Natural Killer-cell Therapy for Acute Myeloid Leukemia

    Sponsor: Radboud University Medical Center. Phase: PHASE1. Conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, Relapsed, Adult

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT06632652: Telenursing System by Providing Health Education and Lifestyle Modification Among Diabetic Patients in Bangladesh

    Sponsor: Hiroshima University. Phase: NA. Conditions: Diabetes Mellitus

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT05809752: A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

    Sponsor: H. Lee Moffitt Cancer Center and Research Institute. Phase: PHASE1. Conditions: Leptomeningeal Disease, Triple Negative Breast Cancer, HER2-positive Breast Cancer

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT01984138: REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

    Sponsor: Polly A. Niravath, MD. Phase: PHASE2. Conditions: Estrogen Receptor Positive Breast Cancer, Breast Cancer

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT04271358: Peer Coaching Intervention in Young Adults With Congenital Heart Disease

    Sponsor: Duke University. Phase: NA. Conditions: Congenital Heart Disease, Congenital Heart Defect

    full page →ctgov ↗
    ›ACTIVE_NOT_RECRUITINGphase readoutNCT05933655: Re-thinking the Role of Peers And Training Patients [RePeAT]

    Sponsor: University of Rochester. Phase: NA. Conditions: Cardiovascular Diseases

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT05904548: Atrial Flutter Ablation in the iCMR

    Sponsor: Imricor Medical Systems. Phase: NA. Conditions: Atrial Flutter Typical

    full page →ctgov ↗
    ›COMPLETEDphase readoutNCT02638155: Food Addiction and Hormone Study

    Sponsor: Texas Tech University. Phase: . Conditions: Disordered Eating

    full page →ctgov ↗
    ›NOT_YET_RECRUITINGphase readoutNCT07543939: Peak Airway Pressure and Respiratory Mechanics During PRVC Ventilation in Laparoscopic Surgery

    Sponsor: Specialized Medical Center (SMC). Phase: . Conditions: Intraoperative Ventilation, Respiratory Mechanics

    full page →ctgov ↗
    ›RECRUITINGphase readoutNCT07252739: KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

    Sponsor: Merck Sharp & Dohme LLC. Phase: PHASE2. Conditions: Malignant Neoplasm

    full page →ctgov ↗
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