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COMPLETEDphase readoutNCT06884670: Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

Sponsor: The First Affiliated Hospital with Nanjing Medical University. Phase: PHASE2. Conditions: Rectal Cancer

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COMPLETEDphase readoutNCT07015970: Real-life Follow-up of the Physical Activity in Type 1 Diabetes Participants Equipped With an Insulin Pump With Hybrid Closed Loop

Sponsor: ISIS Diabete Service. Phase: . Conditions: Diabetes Mellitus Type 1, Glucose Metabolism Disorder, Glycemic Control for Diabetes Mellitus, Fear of Hypoglycemia, Treatment Satisfaction, Quality of Life, Hypoglycaemia

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WITHDRAWNphase readoutNCT04243473: Biopsy Collection for Men Undergoing Brachytherapy for Prostate Cancer

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Phase: . Conditions: Prostate Cancer

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RECRUITINGphase readoutNCT07550673: Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis（UPRISE）

Sponsor: Xijing Hospital of Digestive Diseases. Phase: PHASE4. Conditions: Acute Severe Ulcerative Colitis

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COMPLETEDphase readoutNCT07355673: The Influence of Isolation Techniques in Gingival Irritation During an In-office Bleaching

Sponsor: University of Santiago de Compostela. Phase: NA. Conditions: Gingival Irritation

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NOT_YET_RECRUITINGphase readoutNCT07608341: Influence of Probiotics on Early Gut Microbial Colonization

Sponsor: BioGaia AB. Phase: NA. Conditions: C-Section

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COMPLETEDphase readoutNCT05234554: The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis

Sponsor: Aldeyra Therapeutics, Inc.. Phase: PHASE3. Conditions: Allergic Conjunctivitis

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COMPLETEDphase readoutNCT02771405: Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC

Sponsor: National Hepatology & Tropical Medicine Research Institute. Phase: PHASE3. Conditions: Hepatitis C, Chronic, Hepatocellular Carcinoma

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COMPLETEDphase readoutNCT04291859: Lu AF28996 in Participants With Parkinson's Disease (PD)

Sponsor: H. Lundbeck A/S. Phase: PHASE1. Conditions: Parkinson Disease

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NOT_YET_RECRUITINGphase readoutNCT06951880: A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

Sponsor: AstraZeneca. Phase: PHASE1. Conditions: Healthy Participants

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RECRUITINGphase readoutNCT07483827: A Clinical Trial to Test the Safety, Tolerability, and How the Body Processes CPV-104 in Healthy People and Patients With C3-Glomerulopathy

Sponsor: eleva GmbH. Phase: PHASE1. Conditions: C3 Glomerulopathy (C3G), Healthy Adult Participants

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RECRUITINGphase readoutNCT06888427: Sleep Longitudinal Exploration of the Experience of Patients

Sponsor: Centre Hospitalier Universitaire de Nice. Phase: . Conditions: Sleep

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ACTIVE_NOT_RECRUITINGphase readoutNCT04641442: Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

Sponsor: Novartis Pharmaceuticals. Phase: PHASE2. Conditions: NLRC4-GOF, AIFEC (Autoinflammation With Infantile Enterocolitis), XIAP Deficiency, CDC42 Mutations

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ACTIVE_NOT_RECRUITINGphase readoutNCT02642042: Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer

Sponsor: National Cancer Institute (NCI). Phase: PHASE2. Conditions: KRAS Gene Mutation, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Non-Small Cell Cancer AJCC v7

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COMPLETEDphase readoutNCT07370870: Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?

Sponsor: Henrique Tedesco. Phase: NA. Conditions: Cold Therapy

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COMPLETEDphase readoutNCT03265262: The Basophil Activation Test as a Diagnostic Tool in Pediatric Food Allergy

Sponsor: Assistance Publique Hopitaux De Marseille. Phase: NA. Conditions: FOOD ALLERGY

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RECRUITINGphase readoutNCT06572046: STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies

Sponsor: IRCCS Fondazione Stella Maris. Phase: . Conditions: Hereditary Spastic Paraplegia

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RECRUITINGphase readoutNCT07368946: Phosphate Assessment in Chronic Kidney Disease Patients Study

Sponsor: University of Texas Southwestern Medical Center. Phase: NA. Conditions: Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder

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ACTIVE_NOT_RECRUITINGphase readoutNCT07343427: Impact of GON PRF on Central Sensitization in Migraine Patients

Sponsor: Ankara City Hospital Bilkent. Phase: NA. Conditions: Migraine, Central Sensitization

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ACTIVE_NOT_RECRUITINGphase readoutNCT06150027: Efficacy of a Systematic Referral to Palliative Care of Patients Who Need for Palliative Care During an Unscheduled Visit in Comprehensive Anticancer Centers

Sponsor: Centre Leon Berard. Phase: NA. Conditions: Cancer, Emergencies

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RECRUITINGphase readoutNCT05043870: Combined Immunosuppression for Pediatric Crohn's Disease

Sponsor: Children's Hospital of Fudan University. Phase: PHASE4. Conditions: Crohn Disease, Infliximab, Immunosuppression, Children, Only

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NOT_YET_RECRUITINGphase readoutNCT07573670: A Phase 2 Study of Bcl-2 Inhibitor Combined With Azacitidine for Newly Diagnosed Mixed Phenotype Acute Leukemia

Sponsor: The First Affiliated Hospital of Soochow University. Phase: PHASE2. Conditions: Newly Diagnosed Mixed Phenotype Acute Leukemia

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NOT_YET_RECRUITINGphase readoutNCT07607470: Large Algorithm Setting and Validation Study

Sponsor: Nanopath, Inc. Phase: . Conditions: Bacterial Infections, Bacterial Infections and Mycoses, Infections, Vaginitis, Vaginal Diseases, Genital Diseases, Female, Female Urogenital Diseases, Urogenital Disease, Candidiasis, Mycoses, Vulvovaginitis, Vulvar Diseases, Vaginosis, Bacterial

full page →ctgov ↗

RECRUITINGphase readoutNCT07030673: Early Discontinuation of Antibiotic Therapy in Elderly Patients Hospitalized for a Viral Infection

Sponsor: Centre Hospitalier Universitaire, Amiens. Phase: NA. Conditions: Elderly, Antibiotics Overuse, Viral Infections, PCR Multiplex

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COMPLETEDphase readoutNCT04232969: Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's Disease

Sponsor: University College, London. Phase: PHASE3. Conditions: Parkinson's Disease

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COMPLETEDphase readoutNCT06748469: Efficacy of Pulse Radiofrequency Durations in Lumbosacral Pain

Sponsor: Ankara City Hospital Bilkent. Phase: . Conditions: RADICULAR PAIN

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RECRUITINGphase readoutNCT07367269: Effect of Mandala Coloring on Anxiety, Distress, and Comfort in Breast Cancer Patients Receiving Outpatient Chemotherapy

Sponsor: Artvin Coruh University. Phase: NA. Conditions: Breast Cancer

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RECRUITINGphase readoutNCT07209683: The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults

Sponsor: University of Oklahoma. Phase: NA. Conditions: Cognition, Neurovascular Coupling Mechanism and Cognitive Function, Neurovascular Control, Brain Aging, Brain Activity

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RECRUITINGphase readoutNCT07578454: VRehab-SMA Phase 1.2

Sponsor: University of Oxford. Phase: NA. Conditions: Spinal Muscular Atrophy (SMA)

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ACTIVE_NOT_RECRUITINGphase readoutNCT05338905: Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial

Sponsor: Roswell Park Cancer Institute. Phase: NA. Conditions: Head and Neck Squamous Cell Carcinoma

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ACTIVE_NOT_RECRUITINGphase readoutNCT02313194: Spinal Cord Neuromodulation for Spinal Cord Injury

Sponsor: University of California, Los Angeles. Phase: PHASE1. Conditions: Cervical Spinal Cord Injury, Tetraparesis, Tetraplegia

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RECRUITINGphase readoutNCT07323056: Neoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung Cancer

Sponsor: Shanghai Pulmonary Hospital, Shanghai, China. Phase: PHASE2. Conditions: EGFR-mutant Non-small Cell Lung Cancer, Potentially Resectable

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ACTIVE_NOT_RECRUITINGphase readoutNCT04703322: A Study of Pexidartinib in Tenosynovial Giant Cell Tumor in Japan

Sponsor: Daiichi Sankyo Co., Ltd.. Phase: PHASE2. Conditions: Tenosynovial Giant Cell Tumor

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RECRUITINGphase readoutNCT07597122: MIRNA QUANTIFICATION IN PATIENTS WITH SEPTIC SHOCK

Sponsor: Insel Gruppe AG, University Hospital Bern. Phase: . Conditions: Sepsis and Septic Shock

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COMPLETEDphase readoutNCT06731322: Gut, Inflammation and Nutrition in Adult Patients After Fontan Operation

Sponsor: University Medical Centre Ljubljana. Phase: . Conditions: Fontan Circulation, Fontan Procedure

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RECRUITINGphase readoutNCT04188522: Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition

Sponsor: Johns Hopkins University. Phase: . Conditions: Stroke, Stroke Sequelae, Stroke/Brain Attack

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COMPLETEDphase readoutNCT06893731: Healthcare Utilization and Costs Among Hospitalized Patients With Cardiomyopathy

Sponsor: China National Center for Cardiovascular Diseases. Phase: . Conditions: Cardiomyopathies, Cost

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COMPLETEDphase readoutNCT04474431: Correlation of VEGF-A and Fluid Balance in Septic Shock

Sponsor: University Hospital, Rouen. Phase: NA. Conditions: Septic Shock

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COMPLETEDphase readoutNCT06677931: Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma

Sponsor: Fujian Medical University Union Hospital. Phase: NA. Conditions: Melasma

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RECRUITINGphase readoutNCT06789731: Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments

Sponsor: University of South Dakota. Phase: NA. Conditions: Depression, Anxiety

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ACTIVE_NOT_RECRUITINGphase readoutNCT03428802: Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Sponsor: Rutgers, The State University of New Jersey. Phase: PHASE2. Conditions: BRCA1 Gene Mutation, BRCA2 Gene Mutation, Locally Advanced Solid Neoplasm, Metastatic Malignant Solid Neoplasm, POLD1 Gene Mutation, POLE Gene Mutation, Recurrent Malignant Solid Neoplasm, Recurrent Ovarian Carcinoma, Stage III Breast Cancer AJCC v7, Stage III Ovarian Cancer AJCC v8, Stage IIIA Breast Cancer AJCC v7, Stage IIIA Ovarian Cancer AJCC v8, Stage IIIB Breast Cancer AJCC v7, Stage IIIB Ovarian Cancer AJCC v8, Stage IIIC Breast Cancer AJCC v7, Stage IIIC Ovarian Cancer AJCC v8, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Ovarian Cancer AJCC v8, Stage IVA Ovarian Cancer AJCC v8, Stage IVB Ovarian Cancer AJCC v8

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ACTIVE_NOT_RECRUITINGphase readoutNCT03811002: Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

Sponsor: National Cancer Institute (NCI). Phase: PHASE3. Conditions: Limited Stage Lung Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8

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ACTIVE_NOT_RECRUITINGphase readoutNCT06308653: Psilocybin for Major Depressive Disorder (MDD)

Sponsor: Usona Institute. Phase: PHASE3. Conditions: Depressive Disorder, Major

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ENROLLING_BY_INVITATIONphase readoutNCT07217353: The Use of a Novel Vaginal Speculum for Endometrial Biopsies

Sponsor: Rocky Vista University, LLC. Phase: NA. Conditions: Endometrial Cancer

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NOT_YET_RECRUITINGphase readoutNCT07366645: Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries

Sponsor: Cairo University. Phase: NA. Conditions: Incipient Caries

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RECRUITINGphase readoutNCT05523245: Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI

Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University. Phase: . Conditions: Rectal Cancer

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NOT_YET_RECRUITINGphase readoutNCT07625072: Mental Rehearsal in Emergency Cricothyroidotomy Training

Sponsor: Medical University of Warsaw. Phase: NA. Conditions: Difficult Airway, Medical Training, Airway Management, Cricothyroidotomy

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COMPLETEDphase readoutNCT06060977: A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of IMG-007 in Adult Alopecia Areata Participants

Sponsor: Inmagene LLC. Phase: PHASE1. Conditions: Alopecia Areata (AA)

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RECRUITINGphase readoutNCT04027777: Aktiia OPBM Single-center Prospective Observational Study Against Double Auscultation

Sponsor: Aktiia SA. Phase: NA. Conditions: Blood Pressure

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NOT_YET_RECRUITINGphase readoutNCT07299877: Perineural Dexamethasone, Dexmedetomidine, or Their Combination to Reduces Rebound Pain After Supraclavicular Brachial Plexus Block

Sponsor: Al-Azhar University. Phase: PHASE4. Conditions: Brachial Plexus Blocks

full page →ctgov ↗